Burden of liver diseases in the world
Liver disease accounts for approximately 2 million deaths per year worldwide, 1 million due
to complications of cirrhosis and 1 million due to viral hepatitis and hepatocellular …
to complications of cirrhosis and 1 million due to viral hepatitis and hepatocellular …
l‐ornithine l‐aspartate in acute treatment of severe hepatic encephalopathy: a double‐blind randomized controlled trial
A Jain, BC Sharma, B Mahajan, S Srivastava… - Hepatology, 2022 - journals.lww.com
Conclusions HBsAg‐positive patients with HCC are at high or intermediate risk of HBV
reactivation depending on the type of HCC therapy. Nucleos (t) ide analogue prophylaxis …
reactivation depending on the type of HCC therapy. Nucleos (t) ide analogue prophylaxis …
Off-therapy response after nucleos (t) ide analogue withdrawal in patients with chronic hepatitis B: an international, multicenter, multiethnic cohort (RETRACT-B study)
Background & Aims Functional cure, defined based on hepatitis B surface antigen (HBsAg)
loss, is rare during nucleos (t) ide analogue (NA) therapy and guidelines on finite NA …
loss, is rare during nucleos (t) ide analogue (NA) therapy and guidelines on finite NA …
Fructose promotes leaky gut, endotoxemia, and liver fibrosis through ethanol‐inducible cytochrome P450‐2E1–mediated oxidative and nitrative stress
Fructose intake is known to induce obesity, insulin resistance, metabolic syndrome, and
nonalcoholic fatty liver disease (NAFLD). We aimed to evaluate the effects of fructose …
nonalcoholic fatty liver disease (NAFLD). We aimed to evaluate the effects of fructose …
Limited sustained response after stopping nucleos (t) ide analogues in patients with chronic hepatitis B: results from a randomised controlled trial (Toronto STOP study …
KS Liem, S Fung, DK Wong, C Yim, S Noureldin… - Gut, 2019 - gut.bmj.com
Objective Although most patients with chronic hepatitis B (CHB) reach effective virological
suppression with long-term nucleos (t) ide analogues (NA) therapy, some might not need to …
suppression with long-term nucleos (t) ide analogues (NA) therapy, some might not need to …
Hepatitis B surface antigen seroclearance: immune mechanisms, clinical impact, importance for drug development
I Tout, D Loureiro, A Mansouri, V Soumelis, N Boyer… - Journal of …, 2020 - Elsevier
HBsAg seroclearance occurs rarely in the natural history of chronic hepatitis B (CHB)
infection and is associated with improved clinical outcomes. Many factors are associated …
infection and is associated with improved clinical outcomes. Many factors are associated …
Optimizing systemic therapy for advanced hepatocellular carcinoma: the key role of liver function
The number of effective systemic therapies for the treatment of advanced hepatocellular
carcinoma (HCC) is rapidly increasing, and the advent of immunotherapy has changed the …
carcinoma (HCC) is rapidly increasing, and the advent of immunotherapy has changed the …
Comparison of tenofovir and entecavir on the risk of hepatocellular carcinoma and mortality in treatment-naïve patients with chronic hepatitis B in Korea: a large-scale …
Objective The use of tenofovir (TDF) and entecavir (ETV) in patients with chronic hepatitis B
(CHB) has led to a decrease in the incidence of hepatocellular carcinoma (HCC) and liver …
(CHB) has led to a decrease in the incidence of hepatocellular carcinoma (HCC) and liver …
[PDF][PDF] Hepatitis B treatment: what we know now and what remains to be researched
A Suk‐Fong Lok - Hepatology communications, 2019 - Wiley Online Library
Chronic hepatitis B virus (HBV) infection remains a major global health burden. Currently,
two types of treatment, interferons (IFNs) and nucleos (t) ide analogues (NAs), have been …
two types of treatment, interferons (IFNs) and nucleos (t) ide analogues (NAs), have been …
Similar risk of hepatocellular carcinoma during long-term entecavir or tenofovir therapy in Caucasian patients with chronic hepatitis B
Background & Aims A recent study in Asian patients with chronic hepatitis B (CHB) reported
that the incidence of hepatocellular carcinoma (HCC) was lower in patients treated with …
that the incidence of hepatocellular carcinoma (HCC) was lower in patients treated with …