Fragment-based drug discovery against mycobacteria: the success and challenges

NS Togre, AM Vargas, G Bhargavi… - International Journal of …, 2022 - mdpi.com
The emergence of drug-resistant mycobacteria, including Mycobacterium tuberculosis (Mtb)
and non-tuberculous mycobacteria (NTM), poses an increasing global threat that urgently …

[PDF][PDF] Repurposing of fda-approved drugs against mycobacterium tuberculosis target mma4 and cmaa2

D Umapathy, R Soundhararajan… - … Res. Appl. Chem, 2021 - biointerfaceresearch.com
Tuberculosis (TB) is one of the most dreadful and deadliest diseases, killing millions
annually. Its causative organism is a bacterium called Mycobacterium tuberculosis which …

The correlation of microbiota and host epigenome in tuberculosis

S Tarashi, MD Omrani, A Moshiri, A Fateh… - … : Integrated Studies for a …, 2023 - Springer
Tuberculosis (TB) infection still represents a relevant global health issue affecting millions of
patients worldwide, although some may remain undiagnosed and untreated. The diagnosis …

In silico Functional Annotation and Characterization of Hypothetical Proteins in Cedecea neteri SSMD04: Insights into Pathogenicity and Antibiotic Resistance

S Sharma, P Pandey, J Kaur - 2024 - researchsquare.com
Cedecea neteri strain SSMD04 is a rare gram-negative pathogenic bacterium belonging to
the Enterobacteriaceae family. It is known to cause sporadic acute infections, particularly in …

Epigenetic Modifications in host–Bacterial Dialogues: More than Meets the Eye

S Tarashi, M Karimipoor, SD Siadat, A Fuso - Epigenomics, 2022 - Taylor & Francis
Epigenetic modifications cause phenotypic changes without altering the genotype through
the regulation of gene expression in various life domains. Development of several diseases …

Samira Tarashi, Mir Davood Omrani, Arfa Moshiri, Abolfazl Fateh

SD Siadat, A Fuso - Nima Rezaei Editor - Springer
Tuberculosis (TB) infection still represents a relevant global health issue affecting millions of
patients worldwide, although some may remain undiagnosed and untreated. The diagnosis …

[HTML][HTML] RNA Expression Analysis of Mycobacterial Methyltransferases Genes in Different Resistant Strains of Mycobacterium tuberculosis

S Tarashi, MS Zamani, G Bahramali… - Iranian Biomedical …, 2022 - ncbi.nlm.nih.gov
Background: Tuberculosis infection still represents a global health issue affecting patients
worldwide. Strategies for its control may be not as effective as it should be, specifically in …

Protein kinase J regulates Rv0642c expression and sensitivity to rifampicin of mycobacteria

D Kumar Singh, S Tiwari, K Kripalata, KK Srivastava - bioRxiv, 2021 - biorxiv.org
Mycobacterium tuberculosis (M. tb) persists for long-duration inside the human host in both
active and latent form by modulating the immune response. The mechanisms employed by …

Mechanistic studies of Fusobacterium genetic and defense systems

A Umana Torres - 2020 - vtechworks.lib.vt.edu
Fusobacterium are Gram-negative anaerobic bacteria that colonize a variety of eukaryotes
including cattle and humans. In humans, Fusobacterium coordinates the central architecture …