The aim of this review was to describe the current evidence‐based knowledge of the
epidemiology, prevalence, incidence, risk factors and genetic associations of drug allergy …

Symptoms) is a complex multisystemic severe drug hypersensitivity reaction whose
diagnosis and management are troublesome. It involves the management by different …

Background Cases of severe drug hypersensitivity, demonstrating a variable spectrum of
cutaneous and systemic involvement, are reported under various names, especially drug …

■ Abstract Background: Drug hypersensitivity reactions (DHRs) are among the most
frequent reasons for consultation in allergy departments, and are becoming more common …

Drug hypersensitivity may deprive patients of drug therapy, and occasionally no effective
alternative treatment is available. Successful desensitization has been well documented in …

Severe cutaneous adverse reactions include syndromes such as drug reaction with
eosinophilia and systemic symptoms (DRESS) or drug-induced hypersensitivity syndrome …

Background Generalized bullous fixed drug eruption (GBFDE) is a rare cutaneous adverse
reaction to drugs, and may resemble Stevens–Johnson syndrome (SJS) or toxic epidermal …

Hypersensitivity drug reactions (HDRs) vary over time in frequency, drugs involved, and
clinical entities. Specific reactions are mediated by IgE, other antibody isotypes (IgG or IgM) …

Stevens-Johnson syndrome (SJS) and toxic epidermal necrosis (TEN) are rare but life-
threatening severe cutaneous adverse reactions (SCARs), which are majorly (65–75%) …

Summary Background Stevens–Johnson syndrome (SJS) and toxic epidermal necrolysis
(TEN) are severe cutaneous adverse reactions with high morbidity and mortality. Some …