Cancer immunology and immunotherapy are driving forces of research and development in
oncology, mostly focusing on CD8+ T cells and the tumor microenvironment. Recent …

Epstein–Barr virus (EBV) was the first tumour virus identified in humans. The virus is
primarily associated with lymphomas and epithelial cell cancers. These tumours express …

Highlights•Versatility of CD4 T cells enables different attack modes towards cancer
cells.•Cooperation of CD4 and CD8 T cells renders anti-tumor responses most …

During the past two decades, the paradigm for cancer treatment has evolved from relatively
nonspecific cytotoxic agents to selective, mechanism-based therapeutics. Cancer …

Since the first description in 1989 of CD4‐Fc‐fusion antagonists that inhibit human immune
deficiency virus entry into T cells, Fc‐fusion proteins have been intensely investigated for …

Hematologic parameters are important markers of disease in human and veterinary
medicine. Biomedical research has benefited from mouse models that recapitulate such …

EBV is a prevalent virus, infecting> 90% of the world's population. This is an oncogenic virus
that causes~ 200,000 cancer-related deaths annually. It is, in addition, a significant …

The magnesium transporter 1 (MAGT1) is a critical regulator of basal intracellular free
magnesium (Mg2+) concentrations. Individuals with genetic deficiencies in MAGT1 have …

Abstract The Natural Killer Group 2D (NKG2D) receptor plays an important role in protecting
the host from infections and cancer. By recognizing ligands induced on infected or tumor …

Chronic infection with Plasmodium falciparum was epidemiologically associated with
endemic Burkitt's lymphoma, a mature B cell cancer characterized by chromosome …