Multi-omics approaches for biomarker discovery in early ovarian cancer diagnosis
Y Xiao, M Bi, H Guo, M Li - EBioMedicine, 2022 - thelancet.com
Ovarian cancer (OC) is a heterogeneous disease with the highest mortality rate and the
poorest prognosis among gynecological malignancies. Because of the absence of specific …
poorest prognosis among gynecological malignancies. Because of the absence of specific …
Gastric cancer: where are we heading?
P Petryszyn, N Chapelle, T Matysiak-Budnik - Digestive Diseases, 2020 - karger.com
Background: Despite its decreasing incidence, gastric cancer (GC) remains one of the
leading cancers in the world and an important global healthcare problem due to its overall …
leading cancers in the world and an important global healthcare problem due to its overall …
Large‐scale plasma proteomic profiling identifies a high‐performance biomarker panel for Alzheimer's disease screening and staging
Introduction Blood proteins are emerging as candidate biomarkers for Alzheimer's disease
(AD). We systematically profiled the plasma proteome to identify novel AD blood biomarkers …
(AD). We systematically profiled the plasma proteome to identify novel AD blood biomarkers …
Circulating proteins as diagnostic markers in gastric cancer
Gastric cancer (GC) is a highly malignant disease affecting humans worldwide and has a
poor prognosis. Most GC cases are detected at advanced stages due to the cancer lacking …
poor prognosis. Most GC cases are detected at advanced stages due to the cancer lacking …
The CDCP1 signaling hub: a target for cancer detection and therapeutic intervention
CUB-domain containing protein 1 (CDCP1) is a type I transmembrane glycoprotein that is
upregulated in malignancies of the breast, lung, colorectum, ovary, kidney, liver, pancreas …
upregulated in malignancies of the breast, lung, colorectum, ovary, kidney, liver, pancreas …
The mechanism and role of ADAMTS protein family in osteoarthritis
T Li, J Peng, Q Li, Y Shu, P Zhu, L Hao - Biomolecules, 2022 - mdpi.com
Osteoarthritis (OA) is a principal cause of aches and disability worldwide. It is characterized
by the inflammation of the bone leading to degeneration and loss of cartilage function …
by the inflammation of the bone leading to degeneration and loss of cartilage function …
Challenges and opportunities in clinical applications of blood-based proteomics in cancer
Simple Summary The traditional approach in identifying cancer related protein biomarkers
has focused on evaluation of a single peptide/protein in tissue or circulation. At best, this …
has focused on evaluation of a single peptide/protein in tissue or circulation. At best, this …
Integrated meta-analysis of colorectal cancer public proteomic datasets for biomarker discovery and validation
J Robles, A Prakash, JA Vizcaíno… - PLOS Computational …, 2024 - journals.plos.org
The cancer biomarker field has been an object of thorough investigation in the last decades.
Despite this, colorectal cancer (CRC) heterogeneity makes it challenging to identify and …
Despite this, colorectal cancer (CRC) heterogeneity makes it challenging to identify and …
PPARδ dysregulation of CCL20/CCR6 axis promotes gastric adenocarcinoma carcinogenesis by remodeling gastric tumor microenvironment
Background Peroxisome proliferator-activated receptor delta (PPARδ) promotes
inflammation and carcinogenesis in many organs, but the underlying mechanisms remains …
inflammation and carcinogenesis in many organs, but the underlying mechanisms remains …
Data-driven decision-making for precision diagnosis of digestive diseases
S Jiang, T Wang, KH Zhang - BioMedical Engineering Online, 2023 - Springer
Modern omics technologies can generate massive amounts of biomedical data, providing
unprecedented opportunities for individualized precision medicine. However, traditional …
unprecedented opportunities for individualized precision medicine. However, traditional …