Proportions of circulating T cells with a regulatory cell phenotype increase with HIV-associated immune activation and remain high on antiretroviral therapy
Objective: To examine the relationships between blood CD4 natural regulatory T (T reg)
cells, plasma HIV RNA level, CD4 T-cell count and immune activation in untreated HIV …
cells, plasma HIV RNA level, CD4 T-cell count and immune activation in untreated HIV …
[HTML][HTML] Impact of antiretroviral and tuberculosis therapies on CD4+ and CD8+ HIV/M. tuberculosis-specific T-cell in co-infected subjects
Abstract Background Human Immunodeficiency Virus (HIV) infection is a risk factor for
tuberculosis (TB). Antiretroviral therapy (ART) changed HIV clinical management but it is still …
tuberculosis (TB). Antiretroviral therapy (ART) changed HIV clinical management but it is still …
Restoration of CD4+ responses to copathogens in HIV-infected individuals on antiretroviral therapy is dependent on T cell memory phenotype
Antiretroviral therapy (ART) induces rapid suppression of viral replication and a progressive
replenishment of CD4+ T cells in HIV-infected individuals. However, the effect of ART on …
replenishment of CD4+ T cells in HIV-infected individuals. However, the effect of ART on …
Does CD4+ CD25+ foxp3+ cell (Treg) and IL-10 profile determine susceptibility to immune reconstitution inflammatory syndrome (IRIS) in HIV disease?
HIV-specific T-lymphocyte responses that underlie IRIS are incomplete and largely remain
hypothetical. Of the several mechanisms presented by the host to control host …
hypothetical. Of the several mechanisms presented by the host to control host …
Susceptibility to opportunistic infections in HIV‐infected patients with increased CD4 T‐cell counts on antiretroviral therapy may be predicted by markers of …
MA French, NM Keane, EJ McKinnon, S Phung… - Hiv …, 2007 - Wiley Online Library
Objectives HIV‐infected patients responding to combination antiretroviral therapy (ART) after
experiencing severe immunodeficiency may exhibit persistent immune defects and …
experiencing severe immunodeficiency may exhibit persistent immune defects and …
Cytomegalovirus-Specific Immunity and Protection against Viremia and Disease in HN-Infected Patients in the Era of Highly Active Antiretroviral Therapy
A Weinberg, C Tierney, MA Kendall… - Journal of Infectious …, 2006 - academic.oup.com
To define the immune correlates of protection against cytomegalovirus (CMV) end-organ
disease, CMV-specific interferon (IFN)-γ) I enzyme-linked immunospot (ELISPOT) and CD8+ …
disease, CMV-specific interferon (IFN)-γ) I enzyme-linked immunospot (ELISPOT) and CD8+ …
Restoration of CMV-specific-CD4 T cells with ART occurs early and is greater in those with more advanced immunodeficiency
DC Hsu, SJ Kerr, T Iampornsin, SL Pett… - PloS one, 2013 - journals.plos.org
Objectives Restoration of Cytomegalovirus-specific-CD4 T cell (CMV-Sp-CD4) responses
partly accounts for the reduction of CMV-disease with antiretroviral-therapy (ART), but CMV …
partly accounts for the reduction of CMV-disease with antiretroviral-therapy (ART), but CMV …
Low antigen-specific CD4 T-cell immune responses despite normal absolute CD4 counts after long-term antiretroviral therapy an African cohort
R Nabatanzi, L Bayigga, I Ssinabulya, A Kiragga… - Immunology letters, 2014 - Elsevier
Background CD4 counts guide antiretroviral therapy (ART) initiation and prophylaxis for
opportunistic infections. It is unclear whether normal CD4 counts translate to normalized …
opportunistic infections. It is unclear whether normal CD4 counts translate to normalized …
Antiretroviral therapy in AIDS patients with CMV disease: impact on the survival and long-term treatment outcome
S Sungkanuparph, T Chakriyanuyok, B Butthum - Journal of Infection, 2008 - Elsevier
OBJECTIVES: To determine the impact of antiretroviral therapy (ART) on the long-term
survival of AIDS patients with CMV disease and evaluate long-term outcomes of ART …
survival of AIDS patients with CMV disease and evaluate long-term outcomes of ART …
Dysregulation of CD28 and CTLA‐4 expression by CD4 T cells from previously immunodeficient HIV‐infected patients with sustained virological responses to highly …
SF Stone, P Price, MA French - HIV medicine, 2005 - Wiley Online Library
Objectives Current guidelines recommend commencing highly active antiretroviral therapy
(HAART) in HIV‐infected patients when CD4 T‐cell counts reach 350 cells/μL. However, late …
(HAART) in HIV‐infected patients when CD4 T‐cell counts reach 350 cells/μL. However, late …