Publisher Summary This chapter discusses the interaction of lipids and lipoproteins with the
intercellular matrix of arterial tissue and its' possible role in atherogenesis. It presents the …

Epidemiological and autopsy studies suggest a close link between aging and the clinical
manifestation of atherosclerosis. Several experiments show increased arterial susceptibility …

The hemostatic system is assumed to be similar in children and adults and reference ranges
established for adults are commonly used to evaluate children suspected of having …

This chapter focuses on the basic disease process of atherosclerosis. Atherosclerosis is a
multifactorial disease; aging is only one of the many factors attributing to a process. The …

The changes in levels of glycosaminoglycans (GAGs) of the intima and media of the human
artery in atherosclerosis were determined by a recently introduced two-dimensional …

Congenital and acquired hemostatic disorders present during childhood. An accurate
diagnosis is critically important in order to implement optimal therapy. Over the last century …

Near confluent monolayers of arterial smooth muscle cells derived from Macaca nemestrina
were labeled with Na2 [35S] O4 and the newly synthesized proteoglycans present in the …

A woman, aged 68, with multiple myeloma (immunoglobulin [Ig] A kappa type) developed an
anticoagulant with properties suggestive of heparin. The anticoagulant prolonged the …

Glycosaminoglycan synthesis and secretion by primate arterial smooth muscle have been
examined in cell culture. Mass cultures of diploid primate arterial smooth muscle cells were …

Antithrombin III (ATIII) deficiency has been implicated in adults as a predisposing factor to
thrombosis; however, thromboembolic complications are rare in children with the same …