Information flow, cell types and stereotypy in a full olfactory connectome

P Schlegel, AS Bates, T Stürner, SR Jagannathan… - Elife, 2021 - elifesciences.org
The hemibrain connectome provides large-scale connectivity and morphology information
for the majority of the central brain of Drosophila melanogaster. Using this data set, we …

[HTML][HTML] Efficient information coding and degeneracy in the nervous system

P Seenivasan, R Narayanan - Current opinion in neurobiology, 2022 - Elsevier
Efficient information coding (EIC) is a universal biological framework rooted in the
fundamental principle that system responses should match their natural stimulus statistics for …

Bilateral and unilateral odor processing and odor perception

T Dalal, N Gupta, R Haddad - Communications Biology, 2020 - nature.com
Imagine smelling a novel perfume with only one nostril and then smelling it again with the
other nostril. Clearly, you can tell that it is the same perfume both times. This simple …

The anterior paired lateral neuron normalizes odour-evoked activity in the Drosophila mushroom body calyx

L Prisco, SH Deimel, H Yeliseyeva, A Fiala… - Elife, 2021 - elifesciences.org
To identify and memorize discrete but similar environmental inputs, the brain needs to
distinguish between subtle differences of activity patterns in defined neuronal populations …

Do all mice smell the same? Chemosensory cues from inbred and wild mouse strains elicit stereotypic sensory representations in the accessory olfactory bulb

R Bansal, M Nagel, R Stopkova, Y Sofer, T Kimchi… - BMC biology, 2021 - Springer
Background For many animals, chemosensory cues are vital for social and defensive
interactions and are primarily detected and processed by the vomeronasal system (VNS) …

Algorithmic insights on continual learning from fruit flies

Y Shen, S Dasgupta, S Navlakha - arXiv preprint arXiv:2107.07617, 2021 - arxiv.org
Continual learning in computational systems is challenging due to catastrophic forgetting.
We discovered a two layer neural circuit in the fruit fly olfactory system that addresses this …

Distinct protocerebral neuropils associated with attractive and aversive female-produced odorants in the male moth brain

JH Kymre, XL Liu, E Ian, CN Berge, GR Wang, BG Berg… - Elife, 2021 - elifesciences.org
The pheromone system of heliothine moths is an optimal model for studying principles
underlying higher-order olfactory processing. In Helicoverpa armigera, three male-specific …

Central organization of a high-dimensional odor space

K Endo, H Kazama - Current Opinion in Neurobiology, 2022 - Elsevier
Animals recognize groups and mixtures of odors as a unitary object. This ability is crucial to
generalize known odors to newly encountered ones despite variations. However, it remains …

Mechanisms underlying homeostatic plasticity in the Drosophila mushroom body in vivo

AA Apostolopoulou, AC Lin - Proceedings of the National …, 2020 - National Acad Sciences
Neural network function requires an appropriate balance of excitation and inhibition to be
maintained by homeostatic plasticity. However, little is known about homeostatic …

[HTML][HTML] Synthesis of conserved odor object representations in a random, divergent-convergent network

K Endo, Y Tsuchimoto, H Kazama - Neuron, 2020 - cell.com
Animals are capable of recognizing mixtures and groups of odors as a unitary object.
However, how odor object representations are generated in the brain remains elusive. Here …