The pros and cons of mesenchymal stem cell-based therapies

A Musiał-Wysocka, M Kot, M Majka - Cell transplantation, 2019 - journals.sagepub.com
The need to search for new, alternative treatments for various diseases has prompted
scientists and physicians to focus their attention on regenerative medicine and broadly …

Allogeneic vs. autologous mesenchymal stem/stromal cells in their medication practice

C Li, H Zhao, L Cheng, B Wang - Cell & Bioscience, 2021 - Springer
Mesenchymal stem/stromal cell (MSC)-based therapeutics is already available for treatment
of a range of diseases or medical conditions. Autologous or allogeneic MSCs obtained from …

Clinical trials with mesenchymal stem cells: an update

T Squillaro, G Peluso, U Galderisi - Cell transplantation, 2016 - journals.sagepub.com
In the last year, the promising features of mesenchymal stem cells (MSCs), including their
regenerative properties and ability to differentiate into diverse cell lineages, have generated …

3D bioprinting of heterogeneous constructs providing tissue‐specific microenvironment based on host–guest modulated dynamic hydrogel bioink for osteochondral …

W Dai, L Zhang, Y Yu, W Yan, F Zhao… - Advanced Functional …, 2022 - Wiley Online Library
Abstract 3D bioprinting is a promising strategy to develop heterogeneous constructs that
mimic osteochondral tissue. However, conventional bioprinted hydrogels suffer from …

Mesenchymal stem cell therapy for the treatment of inflammatory diseases: challenges, opportunities, and future perspectives

S Regmi, S Pathak, JO Kim, CS Yong… - European journal of cell …, 2019 - Elsevier
Mesenchymal stem cells (MSCs) are promising alternative agents for the treatment of
inflammatory disorders due to their immunomodulatory functions, and several clinical trials …

Randomized comparison of allogeneic versus autologous mesenchymal stem cells for nonischemic dilated cardiomyopathy: POSEIDON-DCM trial

JM Hare, DL DiFede, AC Rieger, V Florea… - Journal of the American …, 2017 - jacc.org
Background: Although human mesenchymal stem cells (hMSCs) have been tested in
ischemic cardiomyopathy, few studies exist in chronic nonischemic dilated cardiomyopathy …

Comparison of allogeneic vs autologous bone marrow–derived mesenchymal stem cells delivered by transendocardial injection in patients with ischemic …

JM Hare, JE Fishman, G Gerstenblith, DLDF Velazquez… - Jama, 2012 - jamanetwork.com
Context Mesenchymal stem cells (MSCs) are under evaluation as a therapy for ischemic
cardiomyopathy (ICM). Both autologous and allogeneic MSC therapies are possible; …

Different populations and sources of human mesenchymal stem cells (MSC): a comparison of adult and neonatal tissue-derived MSC

R Hass, C Kasper, S Böhm, R Jacobs - Cell Communication and Signaling, 2011 - Springer
The mesenchymal stroma harbors an important population of cells that possess stem cell-
like characteristics including self renewal and differentiation capacities and can be derived …

Use of mesenchymal stem cells for therapy of cardiac disease

V Karantalis, JM Hare - Circulation research, 2015 - Am Heart Assoc
Despite substantial clinical advances over the past 65 years, cardiovascular disease
remains the leading cause of death in America. The past 15 years has witnessed major …

The challenges and promises of allogeneic mesenchymal stem cells for use as a cell-based therapy

J Zhang, X Huang, H Wang, X Liu, T Zhang… - Stem cell research & …, 2015 - Springer
Mesenchymal stem cells (MSCs) are ideal for cell-based therapy in various inflammatory
diseases because of their immunosuppressive and tissue repair properties. Moreover, their …