Self-assisted standing enabled by non-invasive spinal stimulation after spinal cord injury

DG Sayenko, M Rath, AR Ferguson… - Journal of …, 2019 - liebertpub.com
Neuromodulation of spinal networks can improve motor control after spinal cord injury (SCI).
The objectives of this study were to (1) determine whether individuals with chronic paralysis …

Spinal control of motor outputs by intrinsic and externally induced electric field potentials

E Jankowska - Journal of Neurophysiology, 2017 - journals.physiology.org
Despite numerous studies on spinal neuronal systems, several issues regarding their role in
motor behavior remain unresolved. One of these issues is how electric fields associated with …

Repeated transspinal stimulation decreases soleus H-reflex excitability and restores spinal inhibition in human spinal cord injury

M Knikou, LM Murray - PLoS One, 2019 - journals.plos.org
Transcutaneous spinal cord or transspinal stimulation over the thoracolumbar enlargement,
the spinal location of motoneurons innervating leg muscles, modulates neural circuits …

Paired stimulation to promote lasting augmentation of corticospinal circuits

NY Harel, JB Carmel - Neural plasticity, 2016 - Wiley Online Library
After injury, electrical stimulation of the nervous system can augment plasticity of spared or
latent circuits through focal modulation. Pairing stimulation of two parts of a spared circuit …

Transspinal stimulation increases motoneuron output of multiple segments in human spinal cord injury

LM Murray, M Knikou - PloS one, 2019 - journals.plos.org
Targeted neuromodulation strategies that strengthen neuronal activity are in great need for
restoring sensorimotor function after chronic spinal cord injury (SCI). In this study, we …

Neurophysiological changes after paired brain and spinal cord stimulation coupled with locomotor training in human spinal cord injury

TS Pulverenti, M Zaaya, M Grabowski… - Frontiers in …, 2021 - frontiersin.org
Neurophysiological changes that involve activity-dependent neuroplasticity mechanisms via
repeated stimulation and locomotor training are not commonly employed in research even …

Anodal transcutaneous spinal direct current stimulation (tsDCS) selectively inhibits the synaptic efficacy of nociceptive transmission at spinal cord level

C Lenoir, A Jankovski, A Mouraux - Neuroscience, 2018 - Elsevier
Recently studies have aimed at developing transcutaneous spinal direct current stimulation
(tsDCS) as a non-invasive technique to modulate spinal function in humans. Independent …

Adapting human-based transcutaneous spinal cord stimulation to develop a clinically relevant animal model

DC Malloy, M Knikou, MP Côté - Journal of clinical medicine, 2022 - mdpi.com
Transcutaneous spinal cord stimulation (tSCS) as a neuromodulatory strategy has received
great attention as a method to promote functional recovery after spinal cord injury (SCI) …

Transspinal direct current stimulation produces persistent plasticity in human motor pathways

LM Murray, B Tahayori, M Knikou - Scientific reports, 2018 - nature.com
The spinal cord is an integration center for descending, ascending, and segmental neural
signals. Noninvasive transspinal stimulation may thus constitute an effective method for …

Paired associative transspinal and transcortical stimulation produces plasticity in human cortical and spinal neuronal circuits

L Dixon, MM Ibrahim, D Santora… - Journal of …, 2016 - journals.physiology.org
Anatomical, physiological, and functional connectivity exists between the neurons of the
primary motor cortex (M1) and spinal cord. Paired associative stimulation (PAS) produces …