Abstract Social Signal Transduction Theory of Depression is a biologically plausible, multi-
level theory that describes neural, physiologic, molecular, and genomic mechanisms that …

The fundamental framework of steroidogenesis is similar across steroidogenic cells,
especially in initial mitochondrial steps. For instance, the START domain containing protein …

Epidemiologic evidence regarding the effects of in utero exposure to per-and polyfluoroalkyl
substances (PFAS), particularly short-chain PFAS, on fetal reproductive hormones is limited …

The greater prevalence and incidence of Parkinson's disease (PD) in men suggest a
beneficial effect of sex hormones. Neuroactive steroids have neuroprotective activities thus …

In recent years, there has been an increased incidence in several of the most common
reproductive disorders, including hypospadias and cryptorchidism in newborns, and …

Abstract Cytochrome P450 1A (CYP1A), one of the major CYP subfamily in humans, not only
metabolizes xenobiotics including clinical drugs and pollutants in the environment, but also …

Progesterone is essential for pregnancy maintenance and menstrual cycle regulation.
Hormone action has been primarily ascribed to the well-characterized classical signaling …

Although progesterone is a steroid hormone mainly associated with female reproductive
functions, such as uterine receptivity and maintenance of pregnancy, accumulating data …

Pulmonary arterial hypertension (PAH) is a complex disease of multifactorial origin. While
registries have demonstrated that women are more susceptible to the disease, females with …

The adrenal cortex undergoes multiple structural and functional rearrangements to satisfy
the systemic needs for steroids during fetal life, postnatal development, and adulthood. A …