The solubility of proteins plays a key role in determining the physicochemical properties,
processing, sensory attributes, shelf life, and nutritional profile of foods formulated with …

Protein–protein interactions (PPIs) execute many fundamental cellular functions and have
served as prime drug targets over the last two decades. Interfering intracellular PPIs with …

In recent years, the occurrence of a wide variety of drug-resistant diseases has led to an
increase in interest in alternate therapies. Peptide-based drugs as an alternate therapy hold …

Motivation Poor protein solubility hinders the production of many therapeutic and industrially
useful proteins. Experimental efforts to increase solubility are plagued by low success rates …

Background Protein solubility is a precondition for efficient heterologous protein expression
at the basis of most industrial applications and for functional interpretation in basic research …

Enzymes are the natural catalysts that execute biochemical reactions upholding life. Their
natural effectiveness has been fine-tuned as a result of millions of years of natural evolution …

Natural enzymes are delicate biomolecules possessing only marginal thermodynamic
stability. Poorly stable, misfolded, and aggregated proteins lead to huge economic losses in …

Multi-epitope peptide vaccines, as a kind of fusion proteins, usually possess a string-of-
beads structure, consisting of several peptidic epitopes, probably adjuvants and linkers …

The processes used by academic and industrial scientists to discover new drugs have
recently experienced a true renaissance, with many new and exciting techniques being …

Helicobacter pylori is the cunning bacterium that can live in the stomachs of many people
without any symptoms, but gradually can lead to gastric cancer. Due to various obstacles …