Combination therapies of HDAC inhibitors and PD-1 inhibitors

RP Bissonnette, A Rolland, M Gillings - US Patent 10,385,130, 2019 - Google Patents
Provided herein are combinations that include an HDACi and a PD-1 inhibitor that are useful
for treating cancer, including reducing and/or preventing cancer metastasis. The …

Combination therapies of HDAC inhibitors and PD-L1 inhibitors

RP Bissonnette, A Rolland, M Gillings - US Patent 10,385,131, 2019 - Google Patents
US10385131B2 - Combination therapies of HDAC inhibitors and PD-L1 inhibitors - Google
Patents US10385131B2 - Combination therapies of HDAC inhibitors and PD-L1 inhibitors …

Phospholipid ether (PLE) CAR T cell tumor targeting (CTCT) agents

MC Jensen, J Matthaei - US Patent 11,649,288, 2023 - Google Patents
TZCPCKNHXULUIY-RGULYWFUSA-N 1, 2-distearoyl-sn-glycero-3-phosphoserine
Chemical compound CCCCCCCCCCCCCCCCCC (= O) OC [C@ H](COP (O)(= O) OC [C …

Methods of use for CAR T cells

MC Jensen, J Matthaei - US Patent 11,311,576, 2022 - Google Patents
The present disclosure relates to methods of treating a patient with a cancer by
administering to the patient a composition comprising CAR T cells wherein the CAR T cells …

Combination therapies of HDAC inhibitors and PD-1 inhibitors

RP Bissonnette, A Rolland, M Gillings - US Patent 10,287,353, 2019 - Google Patents
2020-10-07 Assigned to HUYA BIOSCIENCES INTERNATIONAL, LLC reassignment HUYA
BIOSCIENCES INTERNATIONAL, LLC ASSIGNMENT OF ASSIGNORS INTEREST (SEE …

Phospholipid ether analogs as cancer-targeting drug vehicles

JP Weichert, A Pinchuk, K Kozak, M Longino… - US Patent …, 2016 - Google Patents
The present invention is directed to therapeutic compounds capable of targeting cancer cells
and cancer stem cells. The present invention is further directed to compositions com prising …

Methods of use for CAR T cells

PS Low, CHU Haiyan, YJ Lu, CP Leamon… - US Patent …, 2023 - Google Patents
The present disclosure relates to methods of treating a patient with a cancer by
administering to the patient a composition comprising CAR T cells wherein the CAR T cells …

Compositions and methods for CAR T cell therapy

PS Low, CHU Haiyan, YG Lee, CP Leamon… - US Patent …, 2023 - Google Patents
The present disclosure relates to methods of treating a patient with a cancer by
administering to the patient a composition comprising CAR T cells and a small molecule …

Modified cytotoxins and their therapeutic use

CE Callmann, MP Thompson, NC Gianneschi… - US Patent …, 2019 - Google Patents
2017-10-26 Assigned to THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
reassignment THE REGENTS OF THE UNIVERSITY OF CALIFORNIA ASSIGNMENT OF …

Phospholipid ether analogs as cancer-targeting drug vehicles

JP Weichert, A Pinchuk, K Kozak, M Longino… - US Patent …, 2018 - Google Patents
The present invention is directed to therapeutic compounds capable of targeting cancer cells
and cancer stem cells. The present invention is further directed to compositions com prising …