Brain-derived neurotrophic factor (BDNF) is one of the most distributed and extensively
studied neurotrophins in the mammalian brain. BDNF signals through the tropomycin …

In addition to producing profound subjective effects following acute administration,
psychedelic compounds can induce beneficial behavioral changes relevant to the treatment …

Serotoninergic hallucinogens include drugs such as lysergic acid diethylamide (LSD),
dimethyltryptamine (DMT) and psilocybin. Recent trials with single/few doses of these …

Ayahuasca is a hallucinogenic botanical beverage originally used by indigenous
Amazonian tribes in religious ceremonies and therapeutic practices. While ethnobotanical …

Serotonin is a key neurotransmitter that is implicated in a wide variety of behavioral and
cognitive phenotypes. Originating in the raphe nuclei, 5-HT neurons project widely to …

Though relatively obscure, N, N-dimethyltryptamine (DMT) is an important molecule in
psychopharmacology as it is the archetype for all indole-containing serotonergic …

N, N-dimethyltryptamine (DMT) is a potent psychedelic naturally produced by many plants
and animals, including humans. Whether or not DMT is significant to mammalian physiology …

Autism spectrum disorders (ASDs) are diagnosed in 1/100 children worldwide, based on two
core symptoms: deficits in social interaction and communication, and stereotyped …

Psychedelics are increasingly being recognized for their potential to treat a wide range of
brain disorders including depression, post‐traumatic stress disorder (PTSD), and substance …

Major depressive disorder is a complex disease resulting from aberrant synaptic plasticity
that may be caused by abnormal serotonergic signaling. Using a combination of behavioral …