Nitric oxide (NO) is a small free radical with critical signaling roles in physiology and
pathophysiology. The generation of sufficient NO levels to regulate the resistance of the …

Over the last decade, a dual character of cell response to oxidative stress, eustress versus
distress, has become increasingly recognized. A growing body of evidence indicates that …

Chronic wounds, such as pressure ulcers, vascular ulcers and diabetic foot ulcers (DFUs),
often stay in a state of pathological inflammation and suffer from persistent infection, excess …

Molecules involved in innate immunity affect sleep and circadian oscillators and vice versa.
Sleep-inducing inflammatory molecules are activated by increased waking activity and …

Summary β‐site amyloid precursor protein cleaving enzyme‐1 (BACE1) research has
historically focused on its actions as the β‐secretase responsible for the production of β …

Nitric Oxide (NO) is a potent signaling molecule involved in the regulation of various cellular
mechanisms and pathways under normal and pathological conditions. NO production, its …

The final outcome of diabetes is chronic complications, of which vascular complications are
the most serious, which is the main cause of death for diabetic patients and the direct cause …

This review describes and summarizes the role of neuronal nitric oxide synthase (nNOS) on
the central nervous system, particularly on brain regions such as the ventrolateral medulla …

Nitric oxide (NO) plays several key roles in the functionality of an organism, and it is usually
released in numerous organs and tissues. There are mainly three isoforms of the enzyme …

The molecular and chemical properties of neuronal nitric oxide synthase (nNOS) have made
it a key mediator in many physiological functions and signaling transduction. The NOS …