Antibiotic resistance in Pseudomonas aeruginosa–Mechanisms, epidemiology and evolution

J Botelho, F Grosso, L Peixe - Drug resistance updates, 2019 - Elsevier
Antibiotics are powerful drugs used in the treatment of bacterial infections. The inappropriate
use of these medicines has driven the dissemination of antibiotic resistance (AR) in most …

Plasmid evolution in carbapenemase‐producing Enterobacteriaceae: a review

K Kopotsa, J Osei Sekyere… - Annals of the New York …, 2019 - Wiley Online Library
Carbapenem‐resistant Enterobacteriaceae (CRE) have been listed by the WHO as high‐
priority pathogens owing to their high association with mortalities and morbidities …

Metagenomic data assembly–the way of decoding unknown microorganisms

AL Lapidus, AI Korobeynikov - Frontiers in Microbiology, 2021 - frontiersin.org
Metagenomics is a segment of conventional microbial genomics dedicated to the
sequencing and analysis of combined genomic DNA of entire environmental samples. The …

Typing methods based on whole genome sequencing data

L Uelze, J Grützke, M Borowiak, JA Hammerl… - One Health …, 2020 - Springer
Whole genome sequencing (WGS) of foodborne pathogens has become an effective
method for investigating the information contained in the genome sequence of bacterial …

mlplasmids: A user-friendly tool to predict plasmid-and chromosome-derived sequences for single species

S Arredondo-Alonso, MRC Rogers… - Microbial …, 2018 - microbiologyresearch.org
Assembly of bacterial short-read whole-genome sequencing data frequently results in
hundreds of contigs for which the origin, plasmid or chromosome, is unclear. Complete …

Plasmid-mediated metronidazole resistance in Clostridioides difficile

IM Boekhoud, BVH Hornung, E Sevilla… - Nature …, 2020 - nature.com
Metronidazole was until recently used as a first-line treatment for potentially life-threatening
Clostridioides difficile (CD) infection. Although cases of metronidazole resistance have been …

Platon: identification and characterization of bacterial plasmid contigs in short-read draft assemblies exploiting protein sequence-based replicon distribution scores

O Schwengers, P Barth, L Falgenhauer… - Microbial …, 2020 - microbiologyresearch.org
Plasmids are extrachromosomal genetic elements that replicate independently of the
chromosome and play a vital role in the environmental adaptation of bacteria. Due to …

Whole-Genome Sequencing of Gram-Negative Bacteria Isolated From Bovine Mastitis and Raw Milk: The First Emergence of Colistin mcr-10 and Fosfomycin fosA5 Resistance …

YH Tartor, NK Abd El-Aziz, RMA Gharieb… - Frontiers in …, 2021 - frontiersin.org
Antimicrobial resistance is a major concern in the dairy industry. This study investigated the
prevalence, antimicrobial resistance phenotypes, and genome sequencing of Gram …

Antimicrobial resistance and virulence of Pseudomonas spp. among healthy animals: concern about exolysin ExlA detection

L Ruiz-Roldán, B Rojo-Bezares, M de Toro, M López… - Scientific reports, 2020 - nature.com
Pseudomonas is a ubiquitous genus that also causes human, animal and plant diseases.
Most studies have focused on clinical P. aeruginosa strains from humans, but they are …

Whole genome-based characterization of multidrug resistant Enterobacter and Klebsiella aerogenes isolates from Lebanon

G Merhi, S Amayri, I Bitar, GF Araj… - Microbiology …, 2023 - Am Soc Microbiol
Enterobacter spp. and Klebsiella aerogenes are rod-shaped Gram-negative opportunistic
pathogens. This study aimed at the molecular and genomic characterization of multidrug …