Engineered hemostatic biomaterials for sealing wounds

H Montazerian, E Davoodi, A Baidya… - Chemical …, 2022 - ACS Publications
Hemostatic biomaterials show great promise in wound control for the treatment of
uncontrolled bleeding associated with damaged tissues, traumatic wounds, and surgical …

Biomaterials and advanced technologies for hemostatic management of bleeding

DSA Hickman, CL Pawlowski, UDS Sekhon… - Advanced …, 2018 - Wiley Online Library
Bleeding complications arising from trauma, surgery, and as congenital, disease‐
associated, or drug‐induced blood disorders can cause significant morbidities and …

Ultra-strong bio-glue from genetically engineered polypeptides

C Ma, J Sun, B Li, Y Feng, Y Sun, L Xiang, B Wu… - Nature …, 2021 - nature.com
The development of biomedical glues is an important, yet challenging task as seemingly
mutually exclusive properties need to be combined in one material, ie strong adhesion and …

Engineering a highly elastic human protein–based sealant for surgical applications

N Annabi, YN Zhang, A Assmann, ES Sani… - Science translational …, 2017 - science.org
Surgical sealants have been used for sealing or reconnecting ruptured tissues but often
have low adhesion, inappropriate mechanical strength, cytotoxicity concerns, and poor …

Bio‐inspired self‐hydrophobized sericin adhesive with tough underwater adhesion enables wound healing and fluid leakage sealing

H Liu, S Qin, J Liu, C Zhou, Y Zhu… - Advanced Functional …, 2022 - Wiley Online Library
Given that adhesion‐resistance of water severely weakens the bonding strength of tissue
adhesives, instant adhesion to wet biological tissue surfaces remains challenging. Inspired …

The chemistry of tissue adhesive materials

PJM Bouten, M Zonjee, J Bender, STK Yauw… - Progress in Polymer …, 2014 - Elsevier
Each year millions of people sustain traumatic or surgical wounds, which require proper
closure. Conventional closure techniques, including suturing and stapling, have many …

VATA: a poly (vinyl alcohol)-and tannic acid-based nontoxic underwater adhesive

D Lee, H Hwang, JS Kim, J Park, D Youn… - … applied materials & …, 2020 - ACS Publications
Few studies aiming to develop a glue with an underwater reusable adhesive property have
been reported because combining the two properties of reusable adhesion and underwater …

A highly adhesive and naturally derived sealant

A Assmann, A Vegh, M Ghasemi-Rad, S Bagherifard… - Biomaterials, 2017 - Elsevier
Conventional surgical techniques to seal and repair defects in highly stressed elastic tissues
are insufficient. Therefore, this study aimed to engineer an inexpensive, highly adhesive …

Marine polysaccharides in pharmaceutical applications: an overview

P Laurienzo - Marine drugs, 2010 - mdpi.com
The enormous variety of polysaccharides that can be extracted from marine plants and
animal organisms or produced by marine bacteria means that the field of marine …

Surgical adhesives: Systematic review of the main types and development forecast

AP Duarte, JF Coelho, JC Bordado, MT Cidade… - Progress in Polymer …, 2012 - Elsevier
Due to several advantages over traditional approaches (eg sutures and staples), surgical
adhesives are excellent materials for wound closure. For several decades intensive …