Reactive oxygen species (ROS) induce carcinogenesis by causing genetic mutations,
activating oncogenes, and increasing oxidative stress, all of which affect cell proliferation …

Cancer metabolism is an essential aspect of tumorigenesis, as cancer cells have increased
energy requirements in comparison to normal cells. Thus, an enhanced metabolism is …

In the bone marrow (BM), breast cancer cells (BCC) can survive in dormancy for decades as
cancer stem cells (CSC), resurging as tertiary metastasis. The endosteal region where BCCs …

Evolutionarily conserved Notch plays a critical role in embryonic development and cellular
self-renewal. It has both tumour suppressor and oncogenic activity, the latter of which is …

Gastric cancer (GC) was the fourth deadliest cancer in the world in 2020, and about 770,000
people died from GC that year. The death of patients with GC is mainly caused by the …

This article reviews mushrooms with anti-breast cancer activity. The mushrooms covered
which are better known include the following: button mushroom Agaricus bisporus, Brazilian …

DNA methyltransferase (DNMT) participates in the transformation or progression of human
cancers by mediating the hypermethylation of cancer suppressors. However, the regulatory …

Breast cancer is the second leading cause of cancer-related death in women and is a
complex disease with high intratumoral and intertumoral heterogeneity. Such heterogeneity …

Accumulating data reveals that tumors possess a specialized subset of cancer cells named
cancer stem cells (CSCs), responsible for metastasis and recurrence of malignancies, with …

Obesity is one of the major modifiable risk factors in breast cancer, with obese adipose
tissue showing a pathological role in breast cancer development and malignancy via the …