Objective The objective of this study is to conduct a systematic review of multi-scale HIV
immunoepidemiological models to improve our understanding of the synergistic impact …

Compared with the existing HIV/AIDS host model that considers only age-since-infection or
only spacial diffusion, we propose a new age–space structured model that incorporating …

After the widespread prevalence of COVID-19 at the end of 2022 in Mainland China, a major
concern is when will the second major outbreak occur and with what prevalence and fatality …

Modelling of infectious disease systems has entered a new era in which disease modellers
are increasingly turning to multiscale modelling to extend traditional modelling frameworks …

Most models of COVID-19 are implemented at a single micro or macro scale, ignoring the
interplay between immune response, viral dynamics, individual infectiousness and …

To investigate the joint impact of infection age, spatial diffusion and SARS-CoV-2 infection
processes on the threshold dynamic of covid-19 transmission among population, we …

Malaria is one of the most common mosquito‐borne diseases widespread in the tropical and
subtropical regions. Few models coupling the within‐host malaria dynamics with the …

The existing combination therapy of HIV antiretroviral drugs can lead to the emergence of
drug-resistant viruses, and cannot effectively block direct cell-to-cell infections, these factors …

This paper models the spread of an SIR-epidemic with infection age in a heterogeneous
complex network and the basic reproduction number is obtained. Next, the accuracy of the …

To study the impact of HIV infection at the individual level on the transmission of HIV/AIDS at
the population level, in this paper, we formulate a multi-scale HIV model coupled with a two …