The role of the microcirculation and integrative cardiovascular physiology in the pathogenesis of ICU-acquired weakness

AA Mendelson, D Erickson, R Villar - Frontiers in Physiology, 2023 - frontiersin.org
Skeletal muscle dysfunction after critical illness, defined as ICU-acquired weakness (ICU-
AW), is a complex and multifactorial syndrome that contributes significantly to long-term …

An integrated view on the oxygenation responses to incremental exercise at the brain, the locomotor and respiratory muscles

J Boone, K Vandekerckhove, I Coomans… - European Journal of …, 2016 - Springer
In the past two decades oxygenation responses to incremental ramp exercise, measured
non-invasively by means of near-infrared spectroscopy at different locations in the body …

Exercise intensity thresholds: identifying the boundaries of sustainable performance.

DA Keir, FY Fontana, TC Robertson… - Medicine and science …, 2015 - europepmc.org
Purpose We tested the hypothesis that CP, RCP, MLSS, and [HHb] BP occur at the same
metabolic intensity by examining the pulmonary oxygen uptake (V) O2p and power output …

Metabolic and performance‐related consequences of exercising at and slightly above MLSS

D Iannetta, EC Inglis, C Fullerton… - … journal of medicine …, 2018 - Wiley Online Library
Exercising at the maximal lactate steady state (MLSS) results in increased but stable
metabolic responses. We tested the hypothesis that even a slight increase above MLSS (10 …

Muscle oxygen saturation rates coincide with lactate-based exercise thresholds

PM Batterson, BS Kirby, G Hasselmann… - European journal of …, 2023 - Springer
Introduction Monitoring muscle metabolic activity via blood lactate is a useful tool for
understanding the physiological response to a given exercise intensity. Recent indications …

[HTML][HTML] Effect of blood flow restriction on tissue oxygenation during knee extension

G Ganesan, JA Cotter, W Reuland… - Medicine and science …, 2015 - ncbi.nlm.nih.gov
Purpose Time-Resolved Near Infrared Spectroscopy (TR-NIRS) was used to quantify tissue
oxy-and deoxy-hemoglobin concentrations ([HbO 2],[HbR]), and O 2 saturation (stO 2) in the …

Muscle deoxygenation in the quadriceps during ramp incremental cycling: Deep vs. superficial heterogeneity

D Okushima, DC Poole, HB Rossiter… - Journal of Applied …, 2015 - journals.physiology.org
Muscle deoxygenation (ie, deoxy [Hb+ Mb]) during exercise assesses the matching of
oxygen delivery (Q̇o2) to oxygen utilization (V̇o2). Until now limitations in near-infrared …

A longitudinal study on the interchangeable use of whole-body and local exercise thresholds in cycling

K Caen, JG Bourgois, E Stassijns, J Boone - European Journal of Applied …, 2022 - Springer
Purpose This study longitudinally examined the interchangeable use of critical power (CP),
the maximal lactate steady state (MLSS) and the respiratory compensation point (RCP)(ie …

Determination of respiratory point compensation in healthy adults: Can non-invasive near-infrared spectroscopy help?

FY Fontana, DA Keir, C Bellotti, GF De Roia… - Journal of science and …, 2015 - Elsevier
Objectives We tested the hypothesis that the respiratory compensation point can be
accurately determined in healthy participants during incremental cycling exercise using non …

Oxygenation threshold derived from near-infrared spectroscopy: reliability and its relationship with the first ventilatory threshold

S van der Zwaard, RT Jaspers, IJ Blokland… - PloS one, 2016 - journals.plos.org
Background Near-infrared spectroscopy (NIRS) measurements of oxygenation reflect O2
delivery and utilization in exercising muscle and may improve detection of a critical exercise …