A review of SARS-CoV-2 and the ongoing clinical trials

YF Tu, CS Chien, AA Yarmishyn, YY Lin… - International journal of …, 2020 - mdpi.com
The sudden outbreak of 2019 novel coronavirus (2019-nCoV, later named SARS-CoV-2) in
Wuhan, China, which rapidly grew into a global pandemic, marked the third introduction of a …

Evolutionary trajectory of SARS-CoV-2 and emerging variants

J Singh, P Pandit, AG McArthur, A Banerjee… - Virology journal, 2021 - Springer
The emergence of a novel coronavirus, severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2), and more recently, the independent evolution of multiple SARS-CoV-2 …

[HTML][HTML] Seasonal human coronavirus antibodies are boosted upon SARS-CoV-2 infection but not associated with protection

EM Anderson, EC Goodwin, A Verma, CP Arevalo… - Cell, 2021 - cell.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has rapidly spread within
the human population. Although SARS-CoV-2 is a novel coronavirus, most humans had …

Seasonal coronavirus protective immunity is short-lasting

AWD Edridge, J Kaczorowska, ACR Hoste, M Bakker… - Nature medicine, 2020 - nature.com
A key unsolved question in the current coronavirus disease 2019 (COVID-19) pandemic is
the duration of acquired immunity. Insights from infections with the four seasonal human …

Bats and coronaviruses

A Banerjee, K Kulcsar, V Misra, M Frieman, K Mossman - Viruses, 2019 - mdpi.com
Bats are speculated to be reservoirs of several emerging viruses including coronaviruses
(CoVs) that cause serious disease in humans and agricultural animals. These include CoVs …

Recombination in Coronaviruses, with a Focus on SARS-CoV-2

D Focosi, F Maggi - Viruses, 2022 - mdpi.com
Recombination is a common evolutionary tool for RNA viruses, and coronaviruses are no
exception. We review here the evidence for recombination in SARS-CoV-2 and reconcile …

[HTML][HTML] Epidemiology, genetic recombination, and pathogenesis of coronaviruses

S Su, G Wong, W Shi, J Liu, ACK Lai, J Zhou, W Liu… - Trends in …, 2016 - cell.com
Human coronaviruses (HCoVs) were first described in the 1960s for patients with the
common cold. Since then, more HCoVs have been discovered, including those that cause …

High-throughput screening and identification of potent broad-spectrum inhibitors of coronaviruses

L Shen, J Niu, C Wang, B Huang, W Wang… - Journal of …, 2019 - Am Soc Microbiol
Coronaviruses (CoVs) act as cross-species viruses and have the potential to spread rapidly
into new host species and cause epidemic diseases. Despite the severe public health threat …

Molecular evolution of human coronavirus genomes

D Forni, R Cagliani, M Clerici, M Sironi - Trends in microbiology, 2017 - cell.com
Human coronaviruses (HCoVs), including SARS-CoV and MERS-CoV, are zoonotic
pathogens that originated in wild animals. HCoVs have large genomes that encode a fixed …

An engineered decoy receptor for SARS-CoV-2 broadly binds protein S sequence variants

KK Chan, TJC Tan, KK Narayanan, E Procko - Science Advances, 2021 - science.org
The spike S of SARS-CoV-2 recognizes ACE2 on the host cell membrane to initiate entry.
Soluble decoy receptors, in which the ACE2 ectodomain is engineered to block S with high …