Beta‐blockers for hypertension

CS Wiysonge, HA Bradley, J Volmink… - Cochrane database …, 2017 - cochranelibrary.com
Background Beta‐blockers refer to a mixed group of drugs with diverse pharmacodynamic
and pharmacokinetic properties. They have shown long‐term beneficial effects on mortality …

Drug-induced obesity and its metabolic consequences: a review with a focus on mechanisms and possible therapeutic options

AA Verhaegen, LF Van Gaal - Journal of endocrinological investigation, 2017 - Springer
Weight gain is a common side effect of many widely used drugs. Weight gain of a few
kilograms to an increase of 10% or more of initial body weight has been described. Not only …

The controversial role of beta-blockers in heart failure with preserved ejection fraction

S Wernhart, M Papathanasiou, T Rassaf… - Pharmacology & …, 2023 - Elsevier
Beta-blocker (BB) therapy is a main pillar in treating patients with heart failure and reduced
ejection fraction and has shown a prognostic benefit. However, evidence for application of …

β2‐adrenoreceptor medications and risk of Parkinson disease

S Searles Nielsen, A Gross… - Annals of …, 2018 - Wiley Online Library
Objective A recent study observed a 2‐fold greater risk of Parkinson disease (PD) in relation
to the β2‐adrenoreceptor antagonist propranolol and a markedly lower risk of PD for the β2 …

Current and emerging classes of pharmacological agents for the management of hypertension

U Ojha, S Ruddaraju, N Sabapathy… - American Journal of …, 2022 - Springer
Cardiovascular disease accounts for more than 17 million deaths globally every year, of
which complications of hypertension account for 9.4 million deaths worldwide. Early …

Association of circulating ketone bodies with functional outcomes after ST-segment elevation myocardial infarction

MSLY de Koning, BD Westenbrink, S Assa… - Journal of the American …, 2021 - jacc.org
Abstract Background Circulating ketone bodies (KBs) are increased in patients with heart
failure (HF), corresponding with increased cardiac KB metabolism and HF severity …

Beta-blockers for atherosclerosis prevention: a missed opportunity?

M Vrablik, A Corsini, E Tůmová - Current Atherosclerosis Reports, 2022 - Springer
Abstract Purpose of Review Current guidelines for the management of arterial hypertension
endorse β-adrenergic receptor blocking agents (beta-blockers, BBs) as being particularly …

Isolated systolic hypertension in young people is not spurious and should be treated: pro side of the argument

CM McEniery, SS Franklin, JR Cockcroft… - Hypertension, 2016 - Am Heart Assoc
269 essential hypertension is a common condition, affecting≈ 25% of the population1, 2
and is the leading cause of death and disability worldwide. 3 no longer viewed as a single …

Lipidomic, metabolomic, and behavior responses of zebrafish (Danio rerio) exposed to environmental levels of the beta blocker atenolol

E Ivantsova, I Konig, CL Souders II, D McNabney… - Science of The Total …, 2023 - Elsevier
Blood pressure medications are used to treat hypertension; however, low concentrations of
beta-blockers in water systems can negatively impact aquatic wildlife. Here, we conducted a …

An overview of hyperinsulinemic‐euglycemic therapy in calcium channel blocker and β‐blocker overdose

JR Krenz, Y Kaakeh - Pharmacotherapy: The Journal of Human …, 2018 - Wiley Online Library
Both calcium channel blockers (CCBs) and β blockers (BBs) are associated with fatal
substance exposures within the United States. Cases of overdose with these agents have …