Anaplastic thyroid carcinoma (ATC), although exceedingly rare, is the most aggressive solid
tumor known. Early studies on the effects of different therapies may be biased by the …

Anaplastic thyroid carcinoma is one of the most aggressive malignancies, with a poor
prognosis. Although rare, representing only 2% of clinically recognized thyroid cancers, the …

BACKGROUND & AIMS: Transforming growth factor (TGF)-β signaling occurs through
Smads 2/3/4, which translocate to the nucleus to regulate transcription; TGF-β has tumor …

Although anaplastic thyroid carcinoma (ATC) is one of the most aggressive malignancies, a
few patients survive for a fairly long time after modern intensive treatment. We tried to identify …

THYROID follicular cell tumors present a unique model for the study of genetic and
environmental factors predisposing to benign nodule formation, well differentiated malignant …

Anaplastic thyroid carcinoma is an extremely aggressive solid tumor that resists most
therapeutic efforts and is almost always fatal. It typically arises as a terminal dedifferentiation …

Background. Anaplastic thyroid cancer ranks among the most lethal of all human
malignancies. Its rarity and rapidly fatal course have made it a difficult cancer to both study …

Studies of multiple markers in tumors are required for adequate biological characterization.
We have characterized the expression of multiple proteins in human ovarian tumors using …

A series of sublines of a murine melanoma B16 of C57BL/6 origin were established and
examined regarding their metastatic capacity and expression of nm23. The number of …

Background In thyroid tumors, the coexistence of well-and poorly differentiated tumor types
has led to the hypothesis that poorly differentiated thyroid tumors develop from well …