[HTML][HTML] Natriuretic Peptide Signaling in Uterine Biology and Preeclampsia
Q Wu - International Journal of Molecular Sciences, 2023 - mdpi.com
Endometrial decidualization is a uterine process essential for spiral artery remodeling,
embryo implantation, and trophoblast invasion. Defects in endometrial decidualization and …
embryo implantation, and trophoblast invasion. Defects in endometrial decidualization and …
Sex-specific genetic architecture of blood pressure
The genetic and genomic basis of sex differences in blood pressure (BP) traits remain
unstudied at scale. Here, we conducted sex-stratified and combined-sex genome-wide …
unstudied at scale. Here, we conducted sex-stratified and combined-sex genome-wide …
Screening embryos for polygenic disease risk: a review of epidemiological, clinical, and ethical considerations
A Capalbo, G de Wert, H Mertes… - Human reproduction …, 2024 - academic.oup.com
BACKGROUND The genetic composition of embryos generated by in vitro fertilization (IVF)
can be examined with preimplantation genetic testing (PGT). Until recently, PGT was limited …
can be examined with preimplantation genetic testing (PGT). Until recently, PGT was limited …
Genetic associations of circulating cardiovascular proteins with gestational hypertension and preeclampsia
Importance Hypertensive disorders of pregnancy (HDPs), including gestational hypertension
and preeclampsia, are important contributors to maternal morbidity and mortality worldwide …
and preeclampsia, are important contributors to maternal morbidity and mortality worldwide …
Preeclampsia prediction using machine learning and polygenic risk scores from clinical and genetic risk factors in early and late pregnancies
VP Kovacheva, BW Eberhard, RY Cohen, M Maher… - …, 2024 - Am Heart Assoc
BACKGROUND: Preeclampsia, a pregnancy-specific condition associated with new-onset
hypertension after 20-weeks gestation, is a leading cause of maternal and neonatal …
hypertension after 20-weeks gestation, is a leading cause of maternal and neonatal …
Proteome-and Transcriptome-Wide Genetic Analysis Identifies Biological Pathways and Candidate Drug Targets for Preeclampsia
BACKGROUND: Preeclampsia is a leading cause of maternal and perinatal morbidity and
mortality. However, the current understanding of its underlying biological pathways remains …
mortality. However, the current understanding of its underlying biological pathways remains …
Hypertensive disorders of pregnancy and cardiovascular disease risk: a Mendelian randomisation study
L Tschiderer, YT van der Schouw, S Burgess… - Heart, 2024 - heart.bmj.com
Objective Observational studies show that hypertensive disorders of pregnancy (HDPs) are
related to unfavourable maternal cardiovascular disease (CVD) risk profiles later in life. We …
related to unfavourable maternal cardiovascular disease (CVD) risk profiles later in life. We …
Using the methylome to predict pre-eclampsia
TJ Kaitu'u-Lino, LA Bartho, S Tong - Nature Medicine, 2023 - nature.com
Using the methylome to predict pre-eclampsia | Nature Medicine Skip to main content Thank
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[HTML][HTML] Parental genetically predicted liability for coronary heart disease and risk of adverse pregnancy outcomes: a cohort study
Background Adverse pregnancy outcomes (APO) may unmask or exacerbate a woman's
underlying risk for coronary heart disease (CHD). We estimated associations of maternal …
underlying risk for coronary heart disease (CHD). We estimated associations of maternal …
Differences in Cardiometabolic Proteins in Pregnancy Prioritize Relevant Targets of Preeclampsia
KJ Lindley, A Perry, M Jacobs, L Petty… - … , and vascular biology, 2024 - Am Heart Assoc
BACKGROUND: Preeclampsia is a hypertensive disorder of pregnancy characterized by
widespread vascular inflammation. It occurs frequently in pregnancy, often without known …
widespread vascular inflammation. It occurs frequently in pregnancy, often without known …