The diseases affecting the retina or uvea (iris, ciliary body, or choroid) generate changes in
the biochemical or protein composition of ocular fluids/tissues due to disruption of blood …

Behçet's disease (BD) is a chronic and rare multisystemic disorder defined by autoimmunity
and inflammatory characteristics, manifested by ocular lesions, recurrent genital and oral …

Peptide‐drug conjugates (PDCs) are an important class of therapeutic agents that combine
one or more active molecules with a short peptide via a biodegradable spacer to generate …

Purpose: To determine whether reproxalap, a novel reactive aldehyde species (RASP)
inhibitor, is safe and effective for the treatment of the signs and symptoms of dry eye disease …

Introduction Dry eye disease (DED) is a common ocular condition with a significant impact
on patients' quality of life. Conventional treatments include behavioral changes, tear …

Purpose: Topical corticosteroids used to treat ocular inflammation are associated with a high
risk of clinically significant toxicities. Therefore, corticosteroid-sparing medications to treat …

Purpose To assess the activity of reproxalap, a novel reactive aldehyde species (RASP)
inhibitor, relative to vehicle in patients with dry eye disease (DED) Design Randomized …

Objectives: Vogt-Koyanagi-Harada syndrome is common autoimmune uveitis that can cause
blindness. Recent studies have shown that plasma exosomes carry disease-related proteins …

Objective To develop evidence-based expert-consensus recommendations for the
management of non-infectious, non-neoplastic, non-demyelinating disease associated …

Background Molecular hydrogen (H 2) has been widely reported to have benefiicial effects
in diverse animal models and human disease through reduction of oxidative stress and …