[HTML][HTML] Modes of action of herbal medicines and plant secondary metabolites

M Wink - Medicines, 2015 - mdpi.com
Plants produce a wide diversity of secondary metabolites (SM) which serve them as defense
compounds against herbivores, and other plants and microbes, but also as signal …

Natural compounds with anti-ageing activity

A Argyropoulou, N Aligiannis, IP Trougakos… - Natural product …, 2013 - pubs.rsc.org
Covering: up to the end of June 2013 Ageing is a complex molecular process driven by
diverse molecular pathways and biochemical events that are promoted by both …

Isoorientin: A dietary flavone with the potential to ameliorate diverse metabolic complications

K Ziqubu, PV Dludla, E Joubert, CJF Muller… - Pharmacological …, 2020 - Elsevier
Isoorientin is a natural C-glucosyl flavone that is generating a lot of interest due to its
multiple pharmacological activities. Increasing experimental data have shown that the robust …

A proanthocyanidin-rich extract from Cassia abbreviata exhibits antioxidant and hepatoprotective activities in vivo

M Sobeh, MF Mahmoud, MAO Abdelfattah… - Journal of …, 2018 - Elsevier
Ethnopharmacological relevance Cassia abbreviata is a small to medium sized branched
umbrella-shaped deciduous tree. It is widely spread in the tropics, especially in Africa …

[HTML][HTML] Caenorhabditis elegans as a Model Organism to Evaluate the Antioxidant Effects of Phytochemicals

B Ayuda-Durán, S González-Manzano… - Molecules, 2020 - mdpi.com
The nematode Caenorhabditis elegans was introduced as a model organism in biological
research by Sydney Brenner in the 1970s. Since then, it has been increasingly used for …

Phenolic compounds from Syzygium jambos (Myrtaceae) exhibit distinct antioxidant and hepatoprotective activities in vivo

M Sobeh, A Esmat, G Petruk, MAO Abdelfattah… - Journal of Functional …, 2018 - Elsevier
Abstract HPLC-PDA-MS/MS analysis of Syzygium jambos leaf extract allowed the
identification of 17 secondary metabolites, including flavonol glycosides, flavonol di …

[HTML][HTML] Aspalathin from rooibos (Aspalathus linearis): a bioactive C-glucosyl dihydrochalcone with potential to target the metabolic syndrome

R Johnson, D de Beer, PV Dludla, D Ferreira… - Planta …, 2018 - thieme-connect.com
Aspalathin is a C-glucosyl dihydrochalcone that is abundantly present in Aspalathus
linearis. This endemic South African plant, belonging to the Cape Floristic region, is normally …

Aspalathin, a dihydrochalcone C‐glucoside, protects H9c2 cardiomyocytes against high glucose induced shifts in substrate preference and apoptosis

R Johnson, P Dludla, E Joubert… - Molecular nutrition & …, 2016 - Wiley Online Library
Scope Energy deprivation in the myocardium is associated with impaired heart function. This
study aims to investigate if aspalathin (ASP) can ameliorate hyperglycemic‐induced shift in …

[HTML][HTML] Anti-oxidative effects of Rooibos tea (Aspalathus linearis) on immobilization-induced oxidative stress in rat brain

IS Hong, HY Lee, HP Kim - PloS one, 2014 - journals.plos.org
Exposure to chronic psychological stress may be related to increased reactive oxygen
species (ROS) or free radicals, and thus, long-term exposure to high levels of oxidative …

Antiaging effects of bioactive molecules isolated from plants and fungi

J Martel, DM Ojcius, YF Ko, CJ Chang… - Medicinal Research …, 2019 - Wiley Online Library
Aging is influenced by many lifestyle choices that are under human control, including
nutrition and exercise. The most effective known antiaging intervention consists of calorie …