Surgery for epilepsy

S West, SJ Nevitt, J Cotton, S Gandhi… - Cochrane Database …, 2019 - cochranelibrary.com
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Genetic landscape of common epilepsies: advancing towards precision in treatment

S Thakran, D Guin, P Singh, P Singh, S Kukal… - International journal of …, 2020 - mdpi.com
Epilepsy, a neurological disease characterized by recurrent seizures, is highly
heterogeneous in nature. Based on the prevalence, epilepsy is classified into two types …

The natural history of epilepsy: an epidemiological view

P Kwan, JW Sander - Journal of Neurology, Neurosurgery & …, 2004 - jnnp.bmj.com
Better information of the natural history of epilepsy has important implications for
understanding the underlying neurobiology, evaluating treatment strategies, and planning …

Phenobarbital for the treatment of epilepsy in the 21st century: a critical review

P Kwan, MJ Brodie - Epilepsia, 2004 - Wiley Online Library
Phenobarbital (PB) is the most widely used antiepileptic drug (AED) in the developing world
and remains a popular choice in many industrialized countries. Meta‐analyses of …

Fever, genes, and epilepsy

S Baulac, I Gourfinkel-An, R Nabbout… - The lancet …, 2004 - thelancet.com
About 13% of patients with epilepsy have a history of febrile seizures (FS). Studies of familial
forms suggest a genetic component to the epidemiological link. Indeed, in certain …

The prion protein knockout mouse: a phenotype under challenge

AD Steele, S Lindquist, A Aguzzi - Prion, 2007 - Taylor & Francis
The key pathogenic event in prion disease involves misfolding and aggregation of the
cellular prion protein (PrP). Beyond this fundamental observation, the mechanism by which …

Characterization of mutations in PRNP (prion) gene and their possible roles in neurodegenerative diseases

E Bagyinszky, VV Giau, YC Youn, SSA An… - … disease and treatment, 2018 - Taylor & Francis
Abnormal prion proteins are responsible for several fatal neurodegenerative diseases in
humans and in animals, including Creutzfeldt–Jakob disease (CJD), Gerstmann–Sträussler …

Genetic association studies in epilepsy:“the truth is out there”

NCK Tan, JC Mulley, SF Berkovic - Epilepsia, 2004 - Wiley Online Library
Success has been achieved in identifying many mutations in rare monogenic epilepsy
syndromes by using linkage analysis, but dissecting the genetic basis of common epilepsy …

[HTML][HTML] Multi-omics in mesial temporal lobe epilepsy with hippocampal sclerosis: Clues into the underlying mechanisms leading to disease

EM Bruxel, DCF Bruno, AM do Canto, JC Geraldis… - Seizure, 2021 - Elsevier
Mesial temporal lobe epilepsy (MTLE) is one of the most common types of focal epilepsy in
the adult population. MTLE is frequently associated with a specific histopathological lesion …

MRI evidence of mesial temporal sclerosis in sporadic “benign” temporal lobe epilepsy

A Labate, P Ventura, A Gambardella, E Le Piane… - Neurology, 2006 - AAN Enterprises
Objective: To determine whether there is MRI-detectable mesial temporal sclerosis (MTS) in
patients with sporadic benign temporal lobe epilepsy (BTLE). Methods: Brain MRIs were …