Dopamine, immunity, and disease

B Channer, SM Matt, EA Nickoloff-Bybel, V Pappa… - Pharmacological …, 2023 - ASPET
The neurotransmitter dopamine is a key factor in central nervous system (CNS) function,
regulating many processes including reward, movement, and cognition. Dopamine also …

Antidepressant effects of a psychedelic experience in a large prospective naturalistic sample

VA Nygart, LM Pommerencke… - Journal of …, 2022 - journals.sagepub.com
Background: Over the last two decades, a number of studies have highlighted the potential
of psychedelic therapy. However, questions remain to what extend these results translate to …

Structural and functional deficits and couplings in the cortico-striato-thalamo-cerebellar circuitry in social anxiety disorder

X Zhang, X Suo, X Yang, H Lai, N Pan, M He… - Translational …, 2022 - nature.com
Although functional and structural abnormalities in brain regions involved in the
neurobiology of fear and anxiety have been observed in patients with social anxiety disorder …

Personality change in a trial of psilocybin therapy v. escitalopram treatment for depression

B Weiss, I Ginige, L Shannon, B Giribaldi… - Psychological …, 2024 - cambridge.org
BackgroundPsilocybin Therapy (PT) is being increasingly studied as a psychiatric
intervention. Personality relates to mental health and can be used to probe the nature of PT's …

A systematic review of the potential effects of medications and drugs of abuse on dopamine transporter imaging using [123I]I-FP-CIT SPECT in routine practice

Y Chahid, ZH Sheikh, M Mitropoulos, J Booij - European journal of nuclear …, 2023 - Springer
Purpose In routine practice, dopamine transporter (DAT) imaging is frequently used as a
diagnostic tool to support the diagnosis of Parkinson's disease or dementia with Lewy …

Application of positron emission tomography in psychiatry—methodological developments and future directions

S Cervenka, A Frick, R Bodén, M Lubberink - Translational Psychiatry, 2022 - nature.com
Mental disorders represent an increasing source of disability and high costs for societies
globally. Molecular imaging techniques such as positron emission tomography (PET) …

Systematic review and meta-analysis on the therapeutic reference range for escitalopram: blood concentrations, clinical effects and serotonin transporter occupancy

L Eichentopf, C Hiemke, A Conca, J Engelmann… - Frontiers in …, 2022 - frontiersin.org
Introduction A titration within a certain therapeutic reference range presupposes a
relationship between the blood concentration and the therapeutic effect of a drug. However …

[HTML][HTML] Horizons in human aging neuroscience: from normal neural aging to mental (Fr) agility

KR Ridderinkhof, HJ Krugers - Frontiers in Human Neuroscience, 2022 - frontiersin.org
While aging is an important risk factor for neurodegenerative disorders such as Alzheimer's
Disease and Parkinson's Dis-ease, age-related cognitive decline can also manifest without …

Update on treatments for anxiety-related disorders

HJ Lee, MB Stein - Current Opinion in Psychiatry, 2023 - journals.lww.com
Pharmacotherapy of anxiety disorders is expanding to novel products. Despite trying other
psychological therapies for anxiety disorders, most therapies were comparable to but not …

Electroacupuncture alleviated depression‐like behaviors in ventromedial prefrontal cortex of chronic unpredictable mild stress‐induced rats: Increasing synaptic …

X Cai, M Wu, Z Zhang, H Liu, S Huang… - CNS Neuroscience …, 2023 - Wiley Online Library
Aims Electroacupuncture (EA) shows advantages in both clinical practice and depression
animal models. Dopaminergic‐related dysfunction in the prefrontal cortex (PFC) may be a …