Nerve repair and regeneration: Biological tubulization limits and future perspectives

M Riccio, A Marchesini, P Pugliese… - Journal of cellular …, 2019 - Wiley Online Library
Peripheral nerve physiology and regeneration has been observed and investigated in
literature but surgical applications to reconstruct and restore motor or sensory functions are …

Application of stem cells, growth factors, small molecules, and biological macromolecules on nerve regeneration: a review and future direction

S Nemati Mahand, N Niknami… - … Journal of Polymeric …, 2024 - Taylor & Francis
The nervous system is a vital component of the human body, and its dysfunction can have
fatal consequences or severe adverse effects. After significant disabling conditions, the …

Proteomics characterization of extracellular vesicles sorted by flow cytometry reveals a disease-specific molecular cross-talk from cerebrospinal fluid and tears in …

D Pieragostino, P Lanuti, I Cicalini, MC Cufaro… - Journal of …, 2019 - Elsevier
Several proteomics studies have been conducted to identify new cerebrospinal fluid (CSF)
biomarkers in Multiple Sclerosis (MuS). However, the complexity of CSF and its invasive …

Regulation of Schwann cell and DRG neurite behaviors within decellularized peripheral nerve matrix

W Xue, Y Kong, R Abu, P Roy, SH Huh… - … applied materials & …, 2022 - ACS Publications
Decellularized nerve hydrogels (dNHs) containing bioactive molecules are promising
biomaterials for peripheral nerve injury (PNI) treatment and have been extensively applied …

The proteome of distal nerves: implication in delayed repair and poor functional recovery

S Guo, RM Moore, MC Charlesworth… - Neural regeneration …, 2022 - journals.lww.com
Chronic denervation is one of the key factors that affect nerve regeneration. Chronic
axotomy deteriorates the distal nerve stump, causes protein changes, and renders the …

Inter-Regional Proteomic Profiling of the Human Brain Using an Optimized Protein Extraction Method from Formalin-Fixed Tissue to Identify Signaling Pathways

JM Davidson, SL Rayner, S Liu, F Cheng… - International Journal of …, 2023 - mdpi.com
Proteomics offers vast potential for studying the molecular regulation of the human brain.
Formalin fixation is a common method for preserving human tissue; however, it presents …

Quantitative mass spectrometry analysis of the injured proximal and distal human digital nerve ends

D Frostadottir, C Welinder, R Perez… - Frontiers in Molecular …, 2024 - frontiersin.org
Introduction Proteomic analysis of injured human peripheral nerves, particularly focusing on
events occurring in the proximal and distal nerve ends, remains relatively underexplored …

A hidden human proteome signature characterizes the epithelial mesenchymal transition program

D Vergara, T Verri, M Damato… - Current …, 2020 - ingentaconnect.com
Background: Molecular changes associated with the initiation of the epithelial to
mesenchymal transition (EMT) program involve alterations of large proteome-based …

Inactivation of vimentin in satellite glial cells affects dorsal root ganglion intermediate filament expression and neuronal axon growth in vitro

A Izmiryan, Z Li, F Nothias, J Eyer, D Paulin… - Molecular and Cellular …, 2021 - Elsevier
Peripheral nerve trauma and regeneration are complex events, and little is known
concerning how occurrences in the distal stump affect the cell body's response to injury …

Intra and inter: Alterations in functional brain resting‐state networks after peripheral nerve injury

XX Xing, XY Hua, MX Zheng, ZZ Ma, BB Huo… - Brain and …, 2020 - Wiley Online Library
Introduction Numerous treatments suggest that brain plasticity changes after peripheral
nerve injury (PNI), and most studies examining functional magnetic resonance imaging …