Psychological stress during childhood and adolescence increases risk of health problems
across the lifecourse, and inflammation is implicated as an underlying mechanism. To …

Inflammation, as a neurobiological consequence of childhood trauma, has frequently been
reported across research, however, recent investigations suggest this relationship may be …

Importance It is unclear whether differences exist in the magnitude and variability of pro-
inflammatory mediators in the different phases of bipolar disorder (BD) and among subjects …

Synapses are well known as the main structures responsible for transmitting information
through the release and recognition of neurotransmitters by pre-and post-synaptic neurons …

A history of Childhood Maltreatment (CM) has been repeatedly associated with an increased
risk of developing bipolar disorders (BD) or schizophrenia (SZ). The impact of severe stress …

Childhood adversity increases the risk of developing psychosis, but the biological
mechanisms involved are unknown. Disaggregating early adverse experiences into core …

Background Patients with schizophrenia display peripheral inflammation but the impact of
illness phase is not clear. Our meta-analysis investigated the difference in CRP levels …

Human endogenous retroviruses (HERVs) are remnants of infections that took place several
million years ago and represent around 8% of the human genome. Despite evidence …

Childhood trauma (CT) has been repeatedly linked to earlier onset and greater severity of
bipolar disorder (BD) in adulthood. However, such knowledge is mostly based on …

BackgroundInflammation is a possible biological mechanism underlying the association
between childhood maltreatment and psychosis. Previous investigations on this regard were …