The gut–liver axis and gut microbiota in health and liver disease

CL Hsu, B Schnabl - Nature Reviews Microbiology, 2023 - nature.com
The trillions of microorganisms in the human intestine are important regulators of health, and
disruptions in the gut microbial communities can cause disease. The gut, liver and immune …

The gut virome: A new microbiome component in health and disease

Z Cao, N Sugimura, E Burgermeister, MP Ebert… - …, 2022 - thelancet.com
The human gastrointestinal tract harbours an abundance of viruses, collectively known as
the gut virome. The gut virome is highly heterogeneous across populations and is linked to …

Gut microbiome, liver immunology, and liver diseases

R Wang, R Tang, B Li, X Ma, B Schnabl… - Cellular & molecular …, 2021 - nature.com
The gut microbiota is a complex and plastic consortium of microorganisms that are intricately
connected with human physiology. The liver is a central immunological organ that is …

Alcohol-associated liver disease

B Mackowiak, Y Fu, L Maccioni… - The Journal of Clinical …, 2024 - Am Soc Clin Investig
Alcohol-associated liver disease (ALD) is a major cause of chronic liver disease worldwide,
and comprises a spectrum of several different disorders, including simple steatosis …

From gut microbiota to host appetite: gut microbiota-derived metabolites as key regulators

H Han, B Yi, R Zhong, M Wang, S Zhang, J Ma, Y Yin… - Microbiome, 2021 - Springer
Feelings of hunger and satiety are the key determinants for maintaining the life of humans
and animals. Disturbed appetite control may disrupt the metabolic health of the host and …

The infant gut virome is associated with preschool asthma risk independently of bacteria

C Leal Rodríguez, SA Shah, MA Rasmussen… - Nature Medicine, 2024 - nature.com
Bacteriophage (also known as phage) communities that inhabit the gut have a major effect
on the structure and functioning of bacterial populations, but their roles and association with …

[HTML][HTML] The microbiota in cirrhosis and its role in hepatic decompensation

J Trebicka, J Macnaughtan, B Schnabl… - Journal of …, 2021 - Elsevier
Cirrhosis–the common end-stage of chronic liver disease–is associated with a cascade of
events, of which intestinal bacterial overgrowth and dysbiosis are central. Bacterial toxins …

Bacteriophages and their potential for treatment of gastrointestinal diseases

Y Duan, R Young, B Schnabl - Nature reviews Gastroenterology & …, 2022 - nature.com
Although bacteriophages have been overshadowed as therapeutic agents by antibiotics for
decades, the emergence of multidrug-resistant bacteria and a better understanding of the …

Intestinal phages interact with bacteria and are involved in human diseases

H Shuwen, D Kefeng - Gut Microbes, 2022 - Taylor & Francis
Phages are the most abundant and diverse biological entities on Earth and exert specific
effects on bacterial hosts. The coexistence of phages and bacteria in the intestinal tract is …

An introduction to next generation sequencing bioinformatic analysis in gut microbiome studies

B Gao, L Chi, Y Zhu, X Shi, P Tu, B Li, J Yin, N Gao… - Biomolecules, 2021 - mdpi.com
The gut microbiome is a microbial ecosystem which expresses 100 times more genes than
the human host and plays an essential role in human health and disease pathogenesis …