Management of epilepsy in pregnancy: a report from the International League Against Epilepsy Task Force on Women and Pregnancy

T Tomson, D Battino, R Bromley, S Kochen… - Epileptic …, 2019 - shs.cairn.info
Management of epilepsy in pregnancy: a report from the International League Against Epilepsy
Task Force on Women and Pregnancy | Cairn.info Cairn.info, Matières à réflexion Cairn.info …

Treatment and care of women with epilepsy before, during, and after pregnancy: a practical guide

B Nucera, F Brigo, E Trinka… - Therapeutic advances in …, 2022 - journals.sagepub.com
Women with epilepsy (WWE) wishing for a child represent a highly relevant subgroup of
epilepsy patients. The treating epileptologist needs to delineate the epilepsy syndrome and …

Comparative risk of major congenital malformations with eight different antiepileptic drugs: a prospective cohort study of the EURAP registry

T Tomson, D Battino, E Bonizzoni, J Craig… - The Lancet …, 2018 - thelancet.com
Background Evidence for the comparative teratogenic risk of antiepileptic drugs is
insufficient, particularly in relation to the dosage used. Therefore, we aimed to compare the …

Dose-dependent risk of malformations with antiepileptic drugs: an analysis of data from the EURAP epilepsy and pregnancy registry

T Tomson, D Battino, E Bonizzoni, J Craig… - The Lancet …, 2011 - thelancet.com
Background Prenatal exposure to antiepileptic drugs is associated with a greater risk of
major congenital malformations, but there is inadequate information on the comparative …

Pre-conception folic acid and multivitamin supplementation for the primary and secondary prevention of neural tube defects and other folic acid-sensitive congenital …

RD Wilson, F Audibert, JA Brock, J Carroll… - Journal of Obstetrics and …, 2015 - Elsevier
Objective To provide updated information on the pre-and post-conception use of oral folic
acid with or without a multivitamin/micronutrient supplement for the prevention of neural tube …

IQ at 6 years after in utero exposure to antiepileptic drugs: a controlled cohort study

GA Baker, RL Bromley, M Briggs, CP Cheyne… - Neurology, 2015 - AAN Enterprises
Objective: To delineate the risk to child IQ associated with frequently prescribed antiepileptic
drugs. Methods: Children born to women with epilepsy (n= 243) and women without …

Malformation risks of antiepileptic drug monotherapies in pregnancy: updated results from the UK and Ireland Epilepsy and Pregnancy Registers

E Campbell, F Kennedy, A Russell… - Journal of Neurology …, 2014 - jnnp.bmj.com
Objectives Antiepileptic drug (AED) exposure during pregnancy increases the risk of major
congenital malformations (MCMs). The magnitude of this risk varies by AED exposure. Here …

[HTML][HTML] Maternal folic acid and multivitamin supplementation: International clinical evidence with considerations for the prevention of folate-sensitive birth defects

RD Wilson, DL O'Connor - Preventive Medicine Reports, 2021 - Elsevier
More evidence is available for maternal intake, absorption, distribution, tissue specific
concentrations, and pregnancy outcomes with folic acid (fortification/supplementation) …

Deficient or excess folic acid supply during pregnancy alter cortical neurodevelopment in mouse offspring

A Harlan De Crescenzo, AA Panoutsopoulos… - Cerebral …, 2021 - academic.oup.com
Folate is an essential micronutrient required for both cellular proliferation through de novo
nucleotide synthesis and epigenetic regulation of gene expression through methylation. This …

The neurology of folic acid deficiency

EH Reynolds - Handbook of clinical neurology, 2014 - Elsevier
The metabolism of folic acid and the metabolism of vitamin B 12 are intimately linked such
that deficiency of either vitamin leads to an identical megaloblastic anemia. The neurologic …