Glucocorticoids are steroid hormones with potent immunosuppressive properties. Their
primary source is the adrenals, where they are generated via de novo synthesis from …

Aggression is a crucial behavior that impacts access to limited resources in different
environmental contexts. Androgens synthesized by the gonads promote aggression during …

The profound programming effects of early life stress (ELS) on brain and behavior are
thought to be primarily mediated by adrenal glucocorticoids (GCs). However, in mice …

Stress increases plasma concentrations of corticosteroids, however, their tissue levels are
unclear. Using a repeated social defeat paradigm, we examined the impact of chronic stress …

Background As a severe complication of sepsis, sepsis-associated encephalopathy (SAE)
usually manifests as impaired learning and memory ability in survivors. Previous studies …

The glucocorticoids (GCs) corticosterone and cortisol and the mineralocorticoid aldosterone
are synthesized and secreted from the adrenal gland into the circulation and then …

Early-life infections can have enduring consequences on brain development and function.
Bacterial infections during development increase the risk for neuropsychiatric disorders later …

Glyphosate, commonly known as Roundup®, is heavily used in Canada, with over 50 million
kilograms purchased annually. Its pre-harvest use results in residues in Canadian food …

Immune activation during early development has long-term effects on health, increasing the
risk for neuropsychiatric disorders (eg, mood disorders, schizophrenia, autism) and immune …

The COVID-19 pandemic is a worldwide pandemic challenge that started in China and
spread to almost all countries. The causative virus was identified as highly contagious and …