Globally, there is a huge unmet need for effective treatments for neurodegenerative
diseases. The complexity of the molecular mechanisms underlying neuronal degeneration …

After more than 100 years of research, the neuropathology of schizophrenia remains
unknown and this is despite the fact that both: Kraepelin, E., 1919/1971. Dementia praecox …

Importance The study provides novel data to inform the mechanisms by which poverty
negatively impacts childhood brain development. Objective To investigate whether the …

Active contour segmentation and its robust implementation using level set methods are well-
established theoretical approaches that have been studied thoroughly in the image analysis …

Introduction Advances in image segmentation of magnetic resonance images (MRI) have
demonstrated that multi-atlas approaches improve segmentation over regular atlas-based …

We evaluate the impact of template choice on template-based segmentation of the
hippocampus in epilepsy. Four dataset-specific strategies are quantitatively contrasted: the …

BackgroundStudies of people with schizophrenia assessed using magnetic resonance
imaging (MRI) usually include patients with first-episode and chronic disease, yet brain …

We developed an anatomical mapping technique to detect hippocampal and ventricular
changes in Alzheimer disease (AD). The resulting maps are sensitive to longitudinal …

Automated MRI-derived measurements of in-vivo human brain volumes provide novel
insights into normal and abnormal neuroanatomy, but little is known about measurement …

This paper studies mathematical methods in the emerging new discipline of Computational
Anatomy. Herein we formalize the Brown/Washington University model of anatomy following …