Crystallization is one of the oldest separation and purification unit operations, and has
recently contributed to significant improvements in producing higher-value products with …

Crystallization is one of the most important unit operations used for the separation and
purification of crystalline solid products. Appropriate design and control of the crystallization …

The academic literature on and industrial practice of control of solution crystallization
processes have seen major advances in the past 15 years that have been enabled by …

Seeding is a significant but challenging task for optimizing crystallization process operation,
product quality, and process efficiency. With the development of modern crystallization …

Secondary nucleation can bring the crystallization process into a more easily controlled
state, and it is playing an important role in controlling crystal size distribution, polymorphism …

Understanding interparticle interactions in powder systems is crucial to pharmaceutical
powder processing. Nevertheless, there remains a great challenge in identifying the key …

Process alternatives for continuous crystallization, ie, cascades of mixed suspension, mixed
product removal crystallizers (MSMPRCs) and plug flow crystallizers (PFCs), as well as …

A continuously seeded l-glutamic acid cooling crystallization process, in a continuous
oscillatory baffled crystallizer, was designed and operated to deliver control over …

Over the past few decades, seeding strategies for solution crystallization processes have
been developed for various applications, and significant improvements in crystal quality and …

Crystallization has been applied to a broad range of industries such as bulk and fine
chemicals and the pharmaceutical and food industries. It is important to strategically control …