Effective drug delivery is important in the treatment of various biomedical conditions, ranging
from autoimmune disorders to cancer and bacterial infections. Nanostructured systems can …

Despite the wide range of diseases affecting the eye, ocular bioavailability remains a
challenge in ophthalmic drug delivery. Nowadays an extensive variety of polymers are being …

Dry eye is a common ocular disease that results in discomfort and impaired vision, impacting
an individual's quality of life. A great number of drugs administered in eye drops to treat dry …

Aim Brinzolamide (BNZ) is a carbonic anhydrase inhibitor commonly used for the treatment
of glaucoma. The aim of this study was to prepare BNZ loaded chitosan-pectin …

Background To date, the rapid clearance from ocular surface has been a huge obstacle for
using eye drops to treat glaucoma, since it has led to the short preocular residence time and …

The sealed anatomical features of the eye and its physiological activity that rapidly removes
drugs are called anatomical and physiological barriers, which are the cause of more than …

We have proposed a metal-organic framework (MOF), NH 2-MIL-88 (Fe), as a novel carrier
for topical drug delivery to the eye. The NH 2-MIL-88 (Fe) particles were prepared via a …

Although oral is the preferred route of administration of pharmaceutical formulations, the
long‐standing challenge for medically active compounds to efficiently cross the mucus layer …

In the field of drug delivery, biodegradable polymeric nanoparticles have attracted a great
deal of research interest due to their potential as an ideal non-toxic vehicle for the delivery of …

Introduction Benzalkonium chloride (BAC) is widely employed as a preservative in eye
drops, which will cause the death of corneal epithelial cells due to ROS production, DNA …