Epilepsy, antiepileptic drugs, and aggression: an evidence-based review

MJ Brodie, F Besag, AB Ettinger, M Mula, G Gobbi… - Pharmacological …, 2016 - ASPET
Antiepileptic drugs (AEDs) have many benefits but also many side effects, including
aggression, agitation, and irritability, in some patients with epilepsy. This article offers a …

Synaptic vesicle glycoprotein 2A ligands in the treatment of epilepsy and beyond

W Löscher, M Gillard, ZA Sands, RM Kaminski… - CNS drugs, 2016 - Springer
The synaptic vesicle glycoprotein SV2A belongs to the major facilitator superfamily (MFS) of
transporters and is an integral constituent of synaptic vesicle membranes. SV2A has been …

Reflex epilepsy: triggers and management strategies

ZV Okudan, Ç Özkara - Neuropsychiatric disease and treatment, 2018 - Taylor & Francis
Reflex epilepsies (REs) are identified as epileptic seizures that are consistently induced by
identifiable and objective-specific triggers, which may be an afferent stimulus or by the …

[HTML][HTML] Generalized versus partial reflex seizures: a review

D Italiano, E Ferlazzo, S Gasparini, E Spina… - Seizure, 2014 - Elsevier
In this review we assess our currently available knowledge about reflex seizures with
special emphasis on the difference between “generalized” reflex seizures induced by visual …

State of the art and challenges in epilepsy—a narrative review

AM Manole, CA Sirbu, MR Mititelu, O Vasiliu… - Journal of Personalized …, 2023 - mdpi.com
Epilepsy is a common condition worldwide, with approximately 50 million people suffering
from it. A single seizure does not mean epilepsy; almost 10% of the population can have a …

Comparative effectiveness of antiepileptic drugs in juvenile myoclonic epilepsy

K Silvennoinen, N de Lange, S Zagaglia… - Epilepsia …, 2019 - Wiley Online Library
Objective To study the effectiveness and tolerability of antiepileptic drugs (AEDs) commonly
used in juvenile myoclonic epilepsy (JME). Methods People with JME were identified from a …

Pharmacological outcomes in juvenile myoclonic epilepsy: Support for sodium valproate

A Chowdhury, MJ Brodie - Epilepsy research, 2016 - Elsevier
Purpose Juvenile myoclonic epilepsy (JME) is one of the most frequently diagnosed of the
idiopathic generalised epilepsy syndromes, but long term outcome data still remain sparse …

Prolonged epileptic discharges predict seizure recurrence in JME: Insights from prolonged ambulatory EEG

F Turco, E Bonanni, C Milano, C Pizzanelli… - …, 2021 - Wiley Online Library
Objective Markers of seizure recurrence are needed to personalize antiseizure medication
(ASM) therapy. In the clinical practice, EEG features are considered to be related to the risk …

Infantile, childhood, and adolescent epilepsies

E Wirrell - CONTINUUM: Lifelong Learning in Neurology, 2016 - journals.lww.com
Abstract Purpose of Review: Infantile, childhood, and adolescent epilepsies comprise a
diverse group of entities. Careful characterization of epilepsy into a specific electroclinical …

Prevalence of juvenile myoclonic epilepsy in people< 30 years of age—A population‐based study in Norway

M Syvertsen, MK Hellum, G Hansen, A Edland… - …, 2017 - Wiley Online Library
Objective Despite juvenile myoclonic epilepsy (JME) being considered one of the most
common epilepsies, population‐based prevalence studies of JME are lacking. Our aim was …