Robustness: linking strain design to viable bioprocesses
Microbial cell factories are becoming increasingly popular for the sustainable production of
various chemicals. Metabolic engineering has led to the design of advanced cell factories; …
various chemicals. Metabolic engineering has led to the design of advanced cell factories; …
The antioxidant, anti-apoptotic, and proliferative potency of argan oil against betamethasone-induced oxidative renal damage in rats
Simple Summary The present study aimed to investigate the protective effect of argan oil
against nephrotoxic effect following overdose and long-term administration of …
against nephrotoxic effect following overdose and long-term administration of …
Application of conditional robust calibration to ordinary differential equations models in computational systems biology: A comparison of two sampling strategies
F Bianconi, C Antonini, L Tomassoni… - IET Systems …, 2020 - Wiley Online Library
Mathematical modelling is a widely used technique for describing the temporal behaviour of
biological systems. One of the most challenging topics in computational systems biology is …
biological systems. One of the most challenging topics in computational systems biology is …
Robust Calibration of High Dimension Nonlinear Dynamical Models for Omics Data: An Application in Cancer Systems Biology
F Bianconi, C Antonini, L Tomassoni… - IEEE Transactions on …, 2018 - ieeexplore.ieee.org
In computational mathematical modeling of biological systems, most model parameters,
such as initial conditions, kinetics, and scale factors, are usually unknown because they …
such as initial conditions, kinetics, and scale factors, are usually unknown because they …
Robustness analysis for quantitative assessment of vaccination effects and SARS-CoV-2 lineages in Italy
C Antonini, S Calandrini, F Bianconi - BMC Infectious Diseases, 2022 - Springer
Abstract Background In Italy, the beginning of 2021 was characterized by the emergence of
new variants of SARS-CoV-2 and by the availability of effective vaccines that contributed to …
new variants of SARS-CoV-2 and by the availability of effective vaccines that contributed to …
Mathematical modeling and robustness analysis to unravel COVID-19 transmission dynamics: the Italy case
C Antonini, S Calandrini, F Stracci, C Dario, F Bianconi - Biology, 2020 - mdpi.com
Simple Summary In the absence of vaccines and antiviral therapies against COVID-19, non-
pharmaceutical interventions represent the only weapon to fight this new coronavirus. In this …
pharmaceutical interventions represent the only weapon to fight this new coronavirus. In this …
CRA toolbox: software package for conditional robustness analysis of cancer systems biology models in MATLAB
Background In cancer research, robustness of a complex biochemical network is one of the
most relevant properties to investigate for the development of novel targeted therapies. In …
most relevant properties to investigate for the development of novel targeted therapies. In …
A new Bayesian methodology for nonlinear model calibration in Computational Systems Biology
F Bianconi, L Tomassoni, C Antonini… - Frontiers in Applied …, 2020 - frontiersin.org
Computational modeling is a common tool to quantitatively describe biological processes.
However, most model parameters are usually unknown because they cannot be directly …
However, most model parameters are usually unknown because they cannot be directly …
[HTML][HTML] Reverse phase protein array (RPPA) combined with computational analysis to unravel relevant prognostic factors in non-small cell lung cancer (NSCLC): a …
V Ludovini, R Chiari, L Tomassoni, C Antonini… - Oncotarget, 2017 - ncbi.nlm.nih.gov
In this work high throughput technology and computational analysis were used to study two
stage IV lung adenocarcinoma patients treated with standard chemotherapy with markedly …
stage IV lung adenocarcinoma patients treated with standard chemotherapy with markedly …