Distinct spatial and temporal roles for Th1, Th2, and Th17 cells in asthma
W Luo, J Hu, W Xu, J Dong - Frontiers in Immunology, 2022 - frontiersin.org
Immune response in the asthmatic respiratory tract is mainly driven by CD4+ T helper (Th)
cells, represented by Th1, Th2, and Th17 cells, especially Th2 cells. Asthma is a …
cells, represented by Th1, Th2, and Th17 cells, especially Th2 cells. Asthma is a …
The role of the immune system in the development of endometriosis
Endometriosis is a chronic disease that affects about 10% of women of reproductive age. It
can contribute to pelvic pain, infertility or other conditions such as asthma, cardiovascular …
can contribute to pelvic pain, infertility or other conditions such as asthma, cardiovascular …
Type 2 immunity: Expanding our view
CM Lloyd, RJ Snelgrove - Science immunology, 2018 - science.org
The classical vision of type 2 immune reactions is that they are characterized by a distinct
cellular and cytokine repertoire that is critical for host resistance against helminthic worm …
cellular and cytokine repertoire that is critical for host resistance against helminthic worm …
Cytokines in sepsis: potent immunoregulators and potential therapeutic targets—an updated view
W Schulte, J Bernhagen, R Bucala - Mediators of inflammation, 2013 - Wiley Online Library
Sepsis and septic shock are among the leading causes of death in intensive care units
worldwide. Numerous studies on their pathophysiology have revealed an imbalance in the …
worldwide. Numerous studies on their pathophysiology have revealed an imbalance in the …
IL-4 in the brain: a cytokine to remember
SP Gadani, JC Cronk, GT Norris… - The journal of immunology, 2012 - journals.aai.org
IL-4 has been extensively studied in the context of its role in immunity. Accumulating
evidence indicates, however, that it also plays a critical role in higher functions of the normal …
evidence indicates, however, that it also plays a critical role in higher functions of the normal …
Interleukins, from 1 to 37, and interferon-γ: receptors, functions, and roles in diseases
M Akdis, S Burgler, R Crameri, T Eiwegger… - Journal of allergy and …, 2011 - Elsevier
Advancing our understanding of mechanisms of immune regulation in allergy, asthma,
autoimmune diseases, tumor development, organ transplantation, and chronic infections …
autoimmune diseases, tumor development, organ transplantation, and chronic infections …
Differentiation of effector CD4 T cell populations
CD4 T cells play critical roles in mediating adaptive immunity to a variety of pathogens. They
are also involved in autoimmunity, asthma, and allergic responses as well as in tumor …
are also involved in autoimmunity, asthma, and allergic responses as well as in tumor …
Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and …
F Sallusto, A Lanzavecchia - The Journal of experimental medicine, 1994 - rupress.org
Using granulocyte/macrophage colony-stimulating factor (GM-CSF) and interleukin 4 we
have established dendritic cell (DC) lines from blood mononuclear cells that maintain the …
have established dendritic cell (DC) lines from blood mononuclear cells that maintain the …
Development of TH1 CD4+ T Cells Through IL-12 Produced by Listeria-Induced Macrophages
CS Hsieh, SE Macatonia, CS Tripp, SF Wolf, A O'Garra… - Science, 1993 - science.org
Development of the appropriate CD4+ T helper (TH) subset during an immune response is
important for disease resolution. With the use of naive, ovalbumin-specific αβ T cell receptor …
important for disease resolution. With the use of naive, ovalbumin-specific αβ T cell receptor …
Cellular responses to interferon-γ
U Boehm, T Klamp, M Groot… - Annual review of …, 1997 - annualreviews.org
▪ Abstract The phytohemagglutinin-induced virus-inhibitor may, however, be produced in
white cells in response to a stimulation of cellular RNA synthesis and may be a feedback …
white cells in response to a stimulation of cellular RNA synthesis and may be a feedback …