Ethical issues when using digital biomarkers and artificial intelligence for the early detection of dementia

E Ford, R Milne, K Curlewis - Wiley Interdisciplinary Reviews …, 2023 - Wiley Online Library
Dementia poses a growing challenge for health services but remains stigmatized and under‐
recognized. Digital technologies to aid the earlier detection of dementia are approaching …

A review of quality of life after predictive testing for and earlier identification of neurodegenerative diseases

JS Paulsen, M Nance, JI Kim, NE Carlozzi… - Progress in …, 2013 - Elsevier
The past decade has witnessed an explosion of evidence suggesting that many
neurodegenerative diseases can be detected years, if not decades, earlier than previously …

[HTML][HTML] Information and communication technology solutions for outdoor navigation in dementia

S Teipel, C Babiloni, J Hoey, J Kaye, T Kirste… - Alzheimer's & …, 2016 - Elsevier
Introduction Information and communication technology (ICT) is potentially mature enough
to empower outdoor and social activities in dementia. However, actual ICT-based devices …

Patient values and preferences regarding prognostic counseling in isolated REM sleep behavior disorder

TR Gossard, LN Teigen, S Yoo, PC Timm, J Jagielski… - Sleep, 2023 - academic.oup.com
Abstract Study Objectives Isolated REM sleep behavior disorder (iRBD) carries a high
lifetime risk for phenoconversion to a defined neurodegenerative disease (NDD) including …

Psychological, behavioral and social effects of disclosing Alzheimer's disease biomarkers to research participants: a systematic review

S Bemelmans, K Tromp, EM Bunnik, RJ Milne… - Alzheimer's research & …, 2016 - Springer
Abstract Background Current Alzheimer's disease (AD) research initiatives focus on
cognitively healthy individuals with biomarkers that are associated with the development of …

Specialist approaches to prognostic counseling in isolated REM sleep behavior disorder

LN Teigen, RR Sharp, JR Hirsch, E Campbell… - Sleep medicine, 2021 - Elsevier
Objectives/background Most middle-aged and older adult patients with isolated (idiopathic)
REM sleep behavior disorder (RBD) eventually develop parkinsonism, dementia with Lewy …

Automated detection of patients with dementia whose symptoms have been identified in primary care but have no formal diagnosis: a retrospective case–control study …

E Ford, J Sheppard, S Oliver, P Rooney, S Banerjee… - BMJ open, 2021 - bmjopen.bmj.com
Objectives UK statistics suggest only two-thirds of patients with dementia get a diagnosis
recorded in primary care. General practitioners (GPs) report barriers to formally diagnosing …

Subjective cognitive decline and APOE ɛ4: a systematic review

JI Ali, CM Smart, JR Gawryluk - Journal of Alzheimer's Disease, 2018 - content.iospress.com
Individuals with subjective cognitive decline (SCD) report self-perceived declines in
cognitive function but perform within normal limits on standardized tests. However, for some …

Self-guided management of exome and whole-genome sequencing results: changing the results return model

JH Yu, SM Jamal, HK Tabor, MJ Bamshad - Genetics in Medicine, 2013 - nature.com
Researchers and clinicians face the practical and ethical challenge of if and how to offer for
return the wide and varied scope of results available from individual exome sequencing and …

Ethical implications of Alzheimer's disease prediction in asymptomatic individuals through artificial intelligence

F Ursin, C Timmermann, F Steger - Diagnostics, 2021 - mdpi.com
Biomarker-based predictive tests for subjectively asymptomatic Alzheimer's disease (AD)
are utilized in research today. Novel applications of artificial intelligence (AI) promise to …