Cell sheet technology: a promising strategy in regenerative medicine

M Li, JUN Ma, Y Gao, LEI Yang - Cytotherapy, 2019 - Elsevier
Regenerative medicine is a burgeoning field that is important to combat challenging
diseases and functional impairments. Compared with traditional cell therapies with evident …

Biomimetic 3D tissue models for advanced high-throughput drug screening

KH Nam, AST Smith, S Lone… - Journal of laboratory …, 2015 - journals.sagepub.com
Most current drug screening assays used to identify new drug candidates are 2D cell-based
systems, even though such in vitro assays do not adequately re-create the in vivo complexity …

[HTML][HTML] Role of regenerative medicine in the treatment of diseases

E Rahmani, M Rezaei, R Tavakoli, E Ghadirzadeh… - Kindle, 2023 - preferpub.org
Regenerative medicine is a rapidly advancing field that aims to restore, replace, or
regenerate damaged tissues and organs using advanced biomedical techniques. Its …

Multi-layer pre-vascularized magnetic cell sheets for bone regeneration

AS Silva, LF Santos, MC Mendes, JF Mano - Biomaterials, 2020 - Elsevier
The lack of effective strategies to produce vascularized 3D bone transplants in vitro,
hampers the development of thick-constructed bone, limiting the translational of lab-based …

Injectable polyaniline nanorods/alginate hydrogel with AAV9-mediated VEGF overexpression for myocardial infarction treatment

C Wu, Y Zhang, Y Xu, L Long, X Hu, J Zhang, Y Wang - Biomaterials, 2023 - Elsevier
Intramyocardial injection of hydrogels possesses great potential in the minimally invasive
treatment of myocardial infarction (MI), but the current injectable hydrogels lack conductivity …

Bioactive Spinal Cord Scaffold Releasing Neurotrophic Exosomes to Promote In Situ Centralis Neuroplasticity

S Mi, Z Chang, X Wang, J Gao, Y Liu… - … Applied Materials & …, 2023 - ACS Publications
Spinal cord injury (SCI), one of the most serious injuries of the central nervous system,
causes physical functional dysfunction and even paralysis in millions of patients. As a matter …

Three-dimensional cardiac tissue fabrication based on cell sheet technology

S Masuda, T Shimizu - Advanced drug delivery reviews, 2016 - Elsevier
Cardiac tissue engineering is a promising therapeutic strategy for severe heart failure.
However, conventional tissue engineering methods by seeding cells into biodegradable …

Porous nanofibrous poly (L-lactic acid) scaffolds supporting cardiovascular progenitor cells for cardiac tissue engineering

Q Liu, S Tian, C Zhao, X Chen, I Lei, Z Wang, PX Ma - Acta Biomaterialia, 2015 - Elsevier
Myocardial infarction (MI) is the irreversible necrosis of heart with approximately 1.5 million
cases every year in the United States. Tissue engineering offers a promising strategy for …

Efficient long-term survival of cell grafts after myocardial infarction with thick viable cardiac tissue entirely from pluripotent stem cells

T Matsuo, H Masumoto, S Tajima, T Ikuno… - Scientific reports, 2015 - nature.com
Poor engraftment of cells after transplantation to the heart is a common and unresolved
problem in the cardiac cell therapies. We previously generated cardiovascular cell sheets …

[HTML][HTML] Therapeutic potential of dental pulp stem cells and their derivatives: Insights from basic research toward clinical applications

SM Yuan, XT Yang, SY Zhang, WD Tian… - World Journal of Stem …, 2022 - ncbi.nlm.nih.gov
For more than 20 years, researchers have isolated and identified postnatal dental pulp stem
cells (DPSCs) from different teeth, including natal teeth, exfoliated deciduous teeth, healthy …