Comprehensive insights into medicinal research on imidazole-based supramolecular complexes

SR Li, YM Tan, L Zhang, CH Zhou - Pharmaceutics, 2023 - mdpi.com
The electron-rich five-membered aromatic aza-heterocyclic imidazole, which contains two
nitrogen atoms, is an important functional fragment widely present in a large number of …

Pincer complexes derived from tridentate Schiff bases for their use as antimicrobial metallopharmaceuticals

A Aragón-Muriel, V Reyes-Márquez… - Inorganics, 2022 - mdpi.com
Within the current challenges in medicinal chemistry, the development of new and better
therapeutic agents effective against infectious diseases produced by bacteria, fungi, viruses …

[HTML][HTML] Synthesis, characterization, and anticancer activity of some metal complexes with a new Schiff base ligand

TA Alorini, AN Al-Hakimi, SES Saeed… - Arabian Journal of …, 2022 - Elsevier
A new Schiff base ligand, 2-((E)-((4-(((E)-benzylidene) amino) phenyl) imino) methyl)-
naphthalene-1-ol, was prepared by the reflux condensation of p-phenylenediamine with 2 …

A facile approach synthesis of benzoylaryl benzimidazole as potential α-amylase and α-glucosidase inhibitor with antioxidant activity

LM Aroua, HR Almuhaylan, FM Alminderej… - Bioorganic …, 2021 - Elsevier
Synthetic routes to a series of benzoylarylbenzimidazol 3a-h have been derived from 3, 4-
diaminobenzophenone and an appropriate arylaldehyde in the presence of ammonium …

[HTML][HTML] Synthesis and characterization of different complexes derived from Schiff base and evaluation as a potential anticancer, antimicrobial, and insecticide agent

LM Aroua, SK Alhag, LA Al-Shuraym… - Saudi Journal of …, 2023 - Elsevier
The condensation of (1H-benzimidazole-2-yl) methanamine, with 2-hydroxy
naphthaldehyde lead to Schiff base ligand (H2L)(1). This was later reacted with metal salts …

Synthesis, Structural Characterization, Cytotoxicity, and Protein/DNA Binding Properties of Pyridoxylidene-Aminoguanidine-Metal (Fe, Co, Zn, Cu) Complexes

V Jevtovic, MSO Alhar, D Milenković… - International journal of …, 2023 - mdpi.com
Pyridoxylidene-aminoguanidine (PLAG) and its transition metal complexes are biologically
active compounds with interesting properties. In this contribution, three new metal-PLAG …

Effect of oxy-vanadium (IV) and oxy-zirconium (IV) ions in O, N-bidentate arylhydrazone complexes on their catalytic and biological potentials that supported via …

MSS Adam, OM El-Hady, MM Makhlouf… - Journal of the Taiwan …, 2022 - Elsevier
Background Based on the high coordination behavior of arylhydrazones, as pincer chelating
agents, the purpose of this research is to study the synthesis, characterization and reactivity …

Synthesis, molecular docking, and bioactivity study of novel hybrid benzimidazole urea derivatives: a promising α-amylase and α-glucosidase inhibitor candidate with …

LM Aroua, AH Alosaimi, FM Alminderej, S Messaoudi… - Pharmaceutics, 2023 - mdpi.com
A novel series of benzimidazole ureas 3a–h were elaborated using 2-(1 H-benzoimidazol-2-
yl) aniline 1 and the appropriate isocyanates 2a–h. The antioxidant and possible …

An experimental and theoretical investigation of antimicrobial and anticancer properties of some new Schiff base complexes

T Alorini, I Daoud, AN Al-Hakimi, F Alminderej… - Research on Chemical …, 2023 - Springer
((E)-(4-((E)-4-chlorobenzylidene) amino) phenyl) imino) methyl) naphthalen-1-ol, a new
Schiff base ligand, was made and then metalated with Mn (II), Co (III), Ni (II), Cu (II) and Zn …

[HTML][HTML] Cytotoxic urea Schiff base complexes for multidrug discovery as anticancer activity and low in vivo oral assessing toxicity

LM Aroua, AN Al-Hakimi, MAM Abdulghani… - Arabian Journal of …, 2022 - Elsevier
Novel mononuclear complexes 2–8 derived from hybrid Urea Schiff base HL were
synthesized using various metal Ni 2+, Fe 3+, Cu 2+, Co 2+, Mn 2+, Zn 2+, and Cr 3+. The …