Sexual differentiation of the human brain: relation to gender identity, sexual orientation and neuropsychiatric disorders

AM Bao, DF Swaab - Frontiers in neuroendocrinology, 2011 - Elsevier
During the intrauterine period a testosterone surge masculinizes the fetal brain, whereas the
absence of such a surge results in a feminine brain. As sexual differentiation of the brain …

The stress system in the human brain in depression and neurodegeneration

DF Swaab, AM Bao, PJ Lucassen - Ageing research reviews, 2005 - Elsevier
Corticotropin-releasing hormone (CRH) plays a central role in the regulation of the
hypothalamic-pituitary-adrenal (HPA)-axis, ie, the final common pathway in the stress …

The stress system in depression and neurodegeneration: focus on the human hypothalamus

AM Bao, G Meynen, DF Swaab - Brain research reviews, 2008 - Elsevier
The stress response is mediated by the hypothalamo–pituitary–adrenal (HPA) system.
Activity of the corticotropin-releasing hormone (CRH) neurons in the hypothalamic …

Sex differences in the circadian profiles of melatonin and cortisol in plasma and urine matrices under constant routine conditions

PJ Gunn, B Middleton, SK Davies… - Chronobiology …, 2016 - Taylor & Francis
Conflicting evidence exists as to whether there are differences between males and females
in circadian timing. The aim of the current study was to assess whether sex differences are …

Occurrence and fate of androgens, estrogens, glucocorticoids and progestagens in two different types of municipal wastewater treatment plants

S Liu, GG Ying, JL Zhao, LJ Zhou, B Yang… - Journal of …, 2012 - pubs.rsc.org
The occurrence and fate of fourteen androgens, four estrogens, five glucocorticoids and five
progestagens were investigated in two different types of wastewater treatment plants (Plant …

Metabolomics reveals altered metabolic pathways in experimental asthma

WE Ho, YJ Xu, F Xu, C Cheng, HY Peh… - American Journal of …, 2013 - atsjournals.org
Metabolomics refers to the comprehensive analysis of metabolites in biological systems, and
has been employed to study patients with asthma based on their urinary metabolite profile …

Кортизол как маркер стресса

АИ Козлов, МА Козлова - Физиология человека, 2014 - elibrary.ru
Рассмотрена роль кортизола (Крт), дегидроэпиандростерона (ДГЭА) и ДГЭА-сульфата
(ДГЭА-С) в реакции стресса. Приведены данные о возрастных, половых и суточных …

Sex differences in stress-related disorders: major depressive disorder, bipolar disorder, and posttraumatic stress disorder

DF Swaab, AM Bao - Handbook of Clinical Neurology, 2020 - Elsevier
Stress-related disorders, such as mood disorders and posttraumatic stress disorder (PTSD),
are more common in women than in men. This sex difference is at least partly due to the …

Measurement of urinary free cortisol by tandem mass spectrometry and comparison with results obtained by gas chromatography-mass spectrometry and two …

L Wood, DH Ducroq, HL Fraser… - Annals of clinical …, 2008 - journals.sagepub.com
Background Determination of urinary free cortisol (UFC) is an important adjunct for the
assessment of adrenal function. In this study, we have analysed cortisol concentrations in …

Reference intervals for the urinary steroid metabolome: The impact of sex, age, day and night time on human adult steroidogenesis

D Ackermann, M Groessl, M Pruijm, B Ponte, G Escher… - PloS one, 2019 - journals.plos.org
Objective Urinary steroid metabolomics by GC-MS is an established method in both clinical
and research settings to describe steroidogenic disorders. However, population-based …