FTD spectrum: Neuroimaging across the FTD spectrum

JL Whitwell - Progress in molecular biology and translational …, 2019 - Elsevier
Frontotemporal dementia is a complex and heterogeneous neurodegenerative disease that
encompasses many clinical syndromes, pathological diseases, and genetic mutations …

Parkinsonism in frontotemporal dementias

JB Rowe - International Review of Neurobiology, 2019 - Elsevier
Frontotemporal dementia is a clinically and pathologically heterogeneous group of
neurodegenerative disorders, with progressive impairment of behavior and language. They …

Reward sensitivity deficits modulated by dopamine are associated with apathy in Parkinson's disease

K Muhammed, S Manohar, M Ben Yehuda, TTJ Chong… - Brain, 2016 - academic.oup.com
Apathy is a debilitating and under-recognized condition that has a significant impact in many
neurodegenerative disorders. In Parkinson's disease, it is now known to contribute to worse …

Disease-specific patterns of cortical and subcortical degeneration in a longitudinal study of Alzheimer's disease and behavioural-variant frontotemporal dementia

R Landin-Romero, F Kumfor, CE Leyton, M Irish… - Neuroimage, 2017 - Elsevier
Abstract Background Clinical differentiation between Alzheimer's disease (AD) and
behavioural-variant frontotemporal dementia (bvFTD) is challenging due to overlapping …

A lesion model of envy and Schadenfreude: legal, deservingness and moral dimensions as revealed by neurodegeneration

H Santamaría-García, S Baez, P Reyes… - Brain, 2017 - academic.oup.com
The study of moral emotions (ie Schadenfreude and envy) is critical to understand the
ecological complexity of everyday interactions between cognitive, affective, and social …

[HTML][HTML] Mental states in moving shapes: distinct cortical and subcortical contributions to theory of mind impairments in dementia

A Synn, A Mothakunnel, F Kumfor… - Journal of …, 2018 - content.iospress.com
Impaired capacity for Theory of Mind (ToM) represents one of the hallmark features of the
behavioral variant of frontotemporal dementia (bvFTD) and is suggested to underpin an …

Fair play: social norm compliance failures in behavioural variant frontotemporal dementia

C O'Callaghan, M Bertoux, M Irish, JM Shine, S Wong… - Brain, 2016 - academic.oup.com
Adherence to social norms is compromised in a variety of neuropsychiatric conditions.
Functional neuroimaging studies have investigated social norm compliance in healthy …

[HTML][HTML] Performance of [18F] flutemetamol amyloid imaging against the neuritic plaque component of CERAD and the current (2012) NIA-AA recommendations for the …

S Salloway, JE Gamez, U Singh, CH Sadowsky… - Alzheimer's & Dementia …, 2017 - Elsevier
Introduction Performance of the amyloid tracer [18 F] flutemetamol was evaluated against
three pathology standard of truth (SoT) measures including neuritic plaques (CERAD …

Cortical and subcortical pathological burden and neuronal loss in an autopsy series of FTLD-TDP-type C

A Kawles, Y Nishihira, A Feldman, N Gill, G Minogue… - Brain, 2022 - academic.oup.com
The TDP-43 type C pathological form of frontotemporal lobar degeneration is characterized
by the presence of immunoreactive TDP-43 short and long dystrophic neurites, neuronal …

[HTML][HTML] Decision-making under ambiguity or risk in individuals with Alzheimer's disease and mild cognitive impairment

T Sun, T Xie, J Wang, L Zhang, Y Tian, K Wang… - Frontiers in …, 2020 - frontiersin.org
Background Making advantageous decisions is essential in everyday life. Our objective was
to assess how patients with mild cognitive impairment (MCI) and Alzheimer's disease (AD) …