Macrophage-mediated inflammation in skin wound healing
A Hassanshahi, M Moradzad, S Ghalamkari, M Fadaei… - Cells, 2022 - mdpi.com
Macrophages are key immune cells that respond to infections, and modulate
pathophysiological conditions such as wound healing. By possessing phagocytic activities …
pathophysiological conditions such as wound healing. By possessing phagocytic activities …
Why venous leg ulcers have difficulty healing: overview on pathophysiology, clinical consequences, and treatment
JD Raffetto, D Ligi, R Maniscalco, RA Khalil… - Journal of clinical …, 2020 - mdpi.com
Venous leg ulcers (VLUs) are one of the most common ulcers of the lower extremity. VLU
affects many individuals worldwide, could pose a significant socioeconomic burden to the …
affects many individuals worldwide, could pose a significant socioeconomic burden to the …
Vascular endothelial growth factor and angiogenesis
ANN Hoeben, B Landuyt, MS Highley, H Wildiers… - Pharmacological …, 2004 - ASPET
Angiogenesis is a hallmark of wound healing, the menstrual cycle, cancer, and various
ischemic and inflammatory diseases. A rich variety of pro-and antiangiogenic molecules …
ischemic and inflammatory diseases. A rich variety of pro-and antiangiogenic molecules …
Macrophages: a review of their role in wound healing and their therapeutic use
RJ Snyder, J Lantis, RS Kirsner, V Shah… - Wound Repair and …, 2016 - Wiley Online Library
Macrophages are mononuclear phagocytes established during embryogenesis and derived
from the yolk sac or the fetal liver but also recruited from the blood and bone marrow under …
from the yolk sac or the fetal liver but also recruited from the blood and bone marrow under …
Why chronic wounds will not heal: a novel hypothesis
T Bjarnsholt, K Kirketerp‐Møller… - Wound repair and …, 2008 - Wiley Online Library
The present paper presents a hypothesis aimed at explaining why venous leg ulcers,
pressure ulcers, and diabetic foot ulcers develop into a chronic state. We propose that the …
pressure ulcers, and diabetic foot ulcers develop into a chronic state. We propose that the …
Zinc in wound healing: theoretical, experimental, and clinical aspects
ABG Lansdown, U Mirastschijski… - Wound repair and …, 2007 - Wiley Online Library
Zinc is an essential trace element in the human body and its importance in health and
disease is appreciated. It serves as a cofactor in numerous transcription factors and enzyme …
disease is appreciated. It serves as a cofactor in numerous transcription factors and enzyme …
Cellular dysfunction in the diabetic fibroblast: impairment in migration, vascular endothelial growth factor production, and response to hypoxia
OZ Lerman, RD Galiano, M Armour, JP Levine… - The American journal of …, 2003 - Elsevier
Although it is known that systemic diseases such as diabetes result in impaired wound
healing, the mechanism for this impairment is not understood. Because fibroblasts are …
healing, the mechanism for this impairment is not understood. Because fibroblasts are …
The enhanced permeability retention effect: a new paradigm for drug targeting in infection
EA Azzopardi, EL Ferguson… - Journal of Antimicrobial …, 2013 - academic.oup.com
Multidrug-resistant, Gram-negative infection is a major global determinant of morbidity,
mortality and cost of care. The advent of nanomedicine has enabled tailored engineering of …
mortality and cost of care. The advent of nanomedicine has enabled tailored engineering of …
Elevated levels of matrix metalloproteinases and chronic wound healing: an updated review of clinical evidence
JL Lazaro, V Izzo, S Meaume, AH Davies… - Journal of wound …, 2016 - magonlinelibrary.com
Objective: In the past 20 years, research and clinical trials on the healing process of chronic
wounds have highlighted the key role of the family of enzymes called matrix …
wounds have highlighted the key role of the family of enzymes called matrix …
[HTML][HTML] Matrix metalloproteinases: the sculptors of chronic cutaneous wounds
VR Krishnaswamy, D Mintz, I Sagi - Biochimica et Biophysica Acta (BBA) …, 2017 - Elsevier
Cutaneous wound healing is a complex mechanism with multiple processes orchestrating
harmoniously for structural and functional restoration of the damaged tissue. Chronic non …
harmoniously for structural and functional restoration of the damaged tissue. Chronic non …