Youth (including both childhood and adolescence) is a period when the brain undergoes
dramatic remodeling and is also a time when neuropsychiatric conditions often emerge …

Distinguishing depression in bipolar disorder (BD) from unipolar depression (UD) solely
based on clinical clues is difficult, which has led to the exploration of promising neural …

Fronto-limbic white matter (WM) abnormalities are assumed to lie at the heart of the
pathophysiology of bipolar disorder (BD); however, diffusion tensor imaging (DTI) studies …

Macroscale white matter pathways are the infrastructure for large-scale communication in
the human brain and a prerequisite for healthy brain function. Disruptions in the brain's …

Objectives Magnetic resonance imaging (MRI) studies comparing bipolar and unipolar
depression characterize pathophysiological differences between these conditions. However …

Background This study aimed to compile and synthesize studies investigating explicit
emotion regulation in patients with bipolar disorder and individuals at risk of developing …

Introduction: Bipolar disorder (BD) is a chronic psychiatric disorder marked by clinical and
pathophysiological heterogeneity. There is a high expectation that personalized approaches …

One of the greatest challenges in providing early effective treatment in mood disorders is the
early differential diagnosis between major depression (MDD) and bipolar disorder (BD). A …

Major depressive disorder (MDD) is associated to affected brain wiring. Little is known
whether these changes are stable over time and hence might represent a biological …

Differential brain structural abnormalities between bipolar disorder (BD) and major
depressive disorder (MDD) may reflect different pathological mechanisms underlying these …