[HTML][HTML] Fast Hebbian plasticity and working memory
Theories and models of working memory (WM) were at least since the mid-1990s dominated
by the persistent activity hypothesis. The past decade has seen rising concerns about the …
by the persistent activity hypothesis. The past decade has seen rising concerns about the …
A thalamic-hippocampal CA1 signal for contextual fear memory suppression, extinction, and discrimination
HC Ratigan, S Krishnan, S Smith… - Nature …, 2023 - nature.com
The adaptive regulation of fear memories is a crucial neural function that prevents
inappropriate fear expression. Fear memories can be acquired through contextual fear …
inappropriate fear expression. Fear memories can be acquired through contextual fear …
Building transformers from neurons and astrocytes
L Kozachkov, KV Kastanenka… - Proceedings of the …, 2023 - National Acad Sciences
Glial cells account for between 50% and 90% of all human brain cells, and serve a variety of
important developmental, structural, and metabolic functions. Recent experimental efforts …
important developmental, structural, and metabolic functions. Recent experimental efforts …
Nonlinear slow-timescale mechanisms in synaptic plasticity
C O'Donnell - Current opinion in neurobiology, 2023 - Elsevier
Learning and memory rely on synapses changing their strengths in response to neural
activity. However, there is a substantial gap between the timescales of neural electrical …
activity. However, there is a substantial gap between the timescales of neural electrical …
A critical role for CaMKII in behavioral timescale synaptic plasticity in hippocampal CA1 pyramidal neurons
Behavioral timescale synaptic plasticity (BTSP) is a type of non-Hebbian synaptic plasticity
reported to underlie place field formation. Despite this important function, the molecular …
reported to underlie place field formation. Despite this important function, the molecular …
Dendritic, delayed, stochastic CaMKII activation in behavioural time scale plasticity
Behavioural time scale plasticity (BTSP) is non-Hebbian plasticity induced by integrating
presynaptic and postsynaptic components separated by a behaviourally relevant time scale …
presynaptic and postsynaptic components separated by a behaviourally relevant time scale …
Structures of channelrhodopsin paralogs in peptidiscs explain their contrasting K+ and Na+ selectivities
Kalium channelrhodopsin 1 from Hyphochytrium catenoides (Hc KCR1) is a light-gated
channel used for optogenetic silencing of mammalian neurons. It selects K+ over Na+ in the …
channel used for optogenetic silencing of mammalian neurons. It selects K+ over Na+ in the …
Volumetric voltage imaging of neuronal populations in the mouse brain by confocal light-field microscopy
L Bai, L Cong, Z Shi, Y Zhao, Y Zhang, B Lu, J Zhang… - Nature …, 2024 - nature.com
Voltage imaging measures neuronal activity directly and holds promise for understanding
information processing within individual neurons and across populations. However, imaging …
information processing within individual neurons and across populations. However, imaging …
[HTML][HTML] Perpetual step-like restructuring of hippocampal circuit dynamics
Summary Representation of the environment by hippocampal populations is known to drift
even within a familiar environment, which could reflect gradual changes in single-cell activity …
even within a familiar environment, which could reflect gradual changes in single-cell activity …
Functional architecture of intracellular oscillations in hippocampal dendrites
Z Liao, KC Gonzalez, DM Li, CM Yang… - Nature …, 2024 - nature.com
Fast electrical signaling in dendrites is central to neural computations that support adaptive
behaviors. Conventional techniques lack temporal and spatial resolution and the ability to …
behaviors. Conventional techniques lack temporal and spatial resolution and the ability to …