The “protein folding problem” consists of three closely related puzzles:(a) What is the folding
code?(b) What is the folding mechanism?(c) Can we predict the native structure of a protein …

The ideas that proteins might possess specific functions without being uniquely folded into
rigid 3D-structures and that these floppy polypeptides might constitute a noticeable part of …

Naturally occurring protein switches have been repurposed for the development of
biosensors and reporters for cellular and clinical applications. However, the number of such …

Sequence alignments unambiguously distinguish between protein pairs of similar and non-
similar structure when the pairwise sequence identity is high (> 40% for long alignments) …

Tissue deposition of soluble proteins as amyloid fibrils underlies a range of fatal diseases.
The two naturally occurring human lysozyme variants are both amyloidogenic, and are …

Molecular self-assembly is becoming an increasingly popular route to new supramolecular
structures and molecular materials1–7. The inspiration for such structures is commonly …

The present study was designed and implemented to modify soy protein isolate (SPI) using
dielectric barrier discharge (DBD) plasma and investigate the effects of this treatment on the …

Background Proteins are involved in many interactions with other proteins leading to
networks that regulate and control a wide variety of physiological processes. Some of these …

Understanding of new materials at the molecular level has become increasingly critical for a
new generation of nanomaterials for nanotechnology, namely, the design, synthesis and …

A variety of nuclear localization signals (NLSs) are experimentally known although only one
motif was available for database searches through PROSITE. We initially collected a set of …