The divided bacterial genome: structure, function, and evolution

GC Dicenzo, TM Finan - Microbiology and Molecular Biology …, 2017 - Am Soc Microbiol
Approximately 10% of bacterial genomes are split between two or more large DNA
fragments, a genome architecture referred to as a multipartite genome. This multipartite …

The bacterial cell cycle, chromosome inheritance and cell growth

R Reyes-Lamothe, DJ Sherratt - Nature Reviews Microbiology, 2019 - nature.com
All viable bacterial cells, whether they divide symmetrically or asymmetrically, must
coordinate their growth, division, cell volume and shape with the inheritance of the genome …

The emergence of Vibrio pathogens in Europe: ecology, evolution, and pathogenesis (Paris, 11–12th March 2015)

FL Roux, KM Wegner, C Baker-Austin… - Frontiers in …, 2015 - frontiersin.org
Global change has caused a worldwide increase in reports of Vibrio-associated diseases
with ecosystem-wide impacts on humans and marine animals. In Europe, higher prevalence …

A checkpoint control orchestrates the replication of the two chromosomes of Vibrio cholerae

ME Val, M Marbouty, F de Lemos Martins… - Science …, 2016 - science.org
Bacteria with multiple chromosomes represent up to 10% of all bacterial species. Unlike
eukaryotes, these bacteria use chromosome-specific initiators for their replication. In all …

The in vivo measurement of replication fork velocity and pausing by lag-time analysis

D Huang, AE Johnson, BS Sim, TW Lo… - Nature …, 2023 - nature.com
An important step towards understanding the mechanistic basis of the central dogma is the
quantitative characterization of the dynamics of nucleic-acid-bound molecular motors in the …

DNA-relay mechanism is sufficient to explain ParA-dependent intracellular transport and patterning of single and multiple cargos

IV Surovtsev, M Campos… - Proceedings of the …, 2016 - National Acad Sciences
Spatial ordering of macromolecular components inside cells is important for cellular
physiology and replication. In bacteria, ParA/B systems are known to generate various …

Cell cycle-coordinated maintenance of the Vibrio bipartite genome

T Niault, J Czarnecki, M Lambérioux, D Mazel… - EcoSal …, 2023 - Am Soc Microbiol
To preserve the integrity of their genome, bacteria rely on several genome maintenance
mechanisms that are co-ordinated with the cell cycle. All members of the Vibrio family have a …

Cyanobacterial multi-copy chromosomes and their replication

S Watanabe - Bioscience, Biotechnology, and Biochemistry, 2020 - academic.oup.com
While the model bacteria Escherichia coli and Bacillus subtilis harbor single chromosomes,
which is known as monoploidy, some freshwater cyanobacteria contain multiple …

Genomic Location of the Major Ribosomal Protein Gene Locus Determines Vibrio cholerae Global Growth and Infectivity

A Soler-Bistue, JA Mondotte, MJ Bland, ME Val… - PLoS …, 2015 - journals.plos.org
The effects on cell physiology of gene order within the bacterial chromosome are poorly
understood. In silico approaches have shown that genes involved in transcription and …

Competitive binding of MatP and topoisomerase IV to the MukB hinge domain

GLM Fisher, JR Bolla, KV Rajasekar, J Mäkelä… - Elife, 2021 - elifesciences.org
Structural Maintenance of Chromosomes (SMC) complexes have ubiquitous roles in
compacting DNA linearly, thereby promoting chromosome organization-segregation …