Background The risk of malignant melanoma in congenital melanocytic naevi (CMN) is a
matter of controversial and ongoing debate. Objectives The purpose of this systematic …

Giant congenital melanocytic nevus is usually defined as a melanocytic lesion present at
birth that will reach a diameter≥ 20 cm in adulthood. Its incidence is estimated in< 1: 20,000 …

BACKGROUND: The diameter of congenital melanocytic nevi (CMN) has served as the lone
criterion for determining risks of adverse outcomes such as melanoma. A standardized …

Congenital melanocytic nevi (CMN) are evident in 1% to 6% of neonates. In some studies,
nevi with clinical, dermatoscopic, and histologic features identical to CMN have had a …

Background Large congenital melanocytic naevi (LCMN), which develop in utero and are
present in approximately one in 20 000 newborns, are associated with markedly increased …

BACKGROUND: There is a dearth of information regarding the occurrence of cutaneous
melanoma in a large cohort of persons with large congenital melanocytic nevi (LCMN) or …

Summary Background Congenital melanocytic naevi (CMNs) can be associated with
abnormalities of the cental nervous system (CNS) and/or with melanoma. Quoted incidences …

Methods A working group of pediatric dermatology experts in the Pediatric Dermatology
Research Alliance convened to investigate current best practices and recommendations for …

Abstract Neurocutaneous melanosis (NCM; MIM# 249400; ORPHA: 2481], first reported by
the Bohemian pathologist Rokitansky in 1861, and now more precisely defined as …

A new or changing melanocytic nevus in a child or adolescent often leads to concern in
parents and physicians. To avoid undue alarm and unnecessary procedures, dermatologists …